Ellis Libby, Coleman Michel P
Cancer Research UK Cancer Survival Group, Non-Communicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Health Stat Q. 2010 Winter(48):81-90. doi: 10.1057/hsq.2010.22.
Cancer survival in Spearhead Primary Care trusts (PCTs) is lower than in the rest of England for most common cancers, but differences are smaller than the more substantial survival gradients between deprived and affluent populations using small-area measures of deprivation. The way in which Spearhead PCTs were designated may give an unduly favourable image of inequalities in cancer survival.
Five-year age-standardised relative survival for 10 common cancers was estimated separately for patients resident in Spearhead local authorities (LAs), Spearhead PCTs, and the rest of England. Differences in survival between Spearhead and other LAs and the corresponding differences between Spearhead and other PCTs were compared.
Cancer survival was consistently lower for patients resident in Spearhead areas than in the rest of England for the majority of cancers, regardless of the geographic unit used. Survival was lower in Spearhead LAs than Spearhead PCTs for 11 of the 16 cancer-sex combinations examined. As a consequence, the survival gap between the Spearhead areas and the rest of England was slightly wider when the definition of Spearhead was based on LAs rather than PCTs, but the two contrasts provide a very similar picture.
Small differences were found between using Spearhead LAs and Spearhead PCTs in the estimation of cancer survival, but results were inconsistent. Although the overlap between the two geographies is imperfect, Spearhead PCTs are appropriate geographic units for monitoring inequalities in cancer survival. However, given the instability of NHS geographical boundaries, Spearhead LAs could be a suitable alternative geographic unit.
在大多数常见癌症中,先锋初级保健信托基金(PCT)辖区内的癌症生存率低于英格兰其他地区,但与使用小区域贫困衡量标准得出的贫困和富裕人群之间更大的生存梯度相比,差异较小。先锋PCT的指定方式可能会给癌症生存不平等带来过度有利的印象。
分别估算了居住在先锋地方当局(LA)、先锋PCT和英格兰其他地区的患者10种常见癌症的五年年龄标准化相对生存率。比较了先锋地区与其他LA之间的生存差异以及先锋地区与其他PCT之间的相应差异。
对于大多数癌症,无论使用何种地理单位,居住在先锋地区的患者的癌症生存率始终低于英格兰其他地区。在研究的16种癌症-性别组合中,有11种先锋LA的生存率低于先锋PCT。因此,当先锋的定义基于LA而非PCT时,先锋地区与英格兰其他地区之间的生存差距略大,但两种对比呈现出非常相似的情况。
在癌症生存率估计中,使用先锋LA和先锋PCT之间存在细微差异,但结果不一致。尽管这两个地理区域之间的重叠并不完美,但先锋PCT是监测癌症生存不平等的合适地理单位。然而,鉴于国民保健服务(NHS)地理边界的不稳定性,先锋LA可能是一个合适的替代地理单位。