Casasola R J
Tayside Cancer Centre, Ninewells Hospital, Dundee, UK.
J R Coll Physicians Edinb. 2010 Dec;40(4):343-5; quiz 345. doi: 10.4997/JRCPE.2010.423.
Head and neck cancer is traditionally thought of as being a disease associated with alcohol and tobacco abuse and deprivation. It was the fourth most common cancer in males in Scotland in 2000 and just over 1,000 cases were diagnosed in 2007. As smoking becomes less prevalent, a fall in the incidence of head and neck cancer could be anticipated; however, increasing evidence of other aetiological factors contributing to the diagnosis of head and neck cancer, particularly oropharyngeal cancer in non-smoking, little-drinking populations, is impacting on that perception. This review will aim to look at current aetiological factors for head and neck cancer, along with current therapeutic modalities in treatment of this disease.
传统上认为头颈癌是一种与酗酒、吸烟及贫困相关的疾病。2000年,它是苏格兰男性中第四大常见癌症,2007年确诊病例刚超过1000例。随着吸烟变得不那么普遍,可以预期头颈癌发病率会下降;然而,越来越多的证据表明,其他病因因素也会导致头颈癌的诊断,尤其是在不吸烟、少量饮酒人群中的口咽癌,这正在影响人们的这种认知。本综述旨在探讨头颈癌目前的病因因素以及该疾病当前的治疗方式。