Institute of Applied Mechanics, National Taiwan University, Taipei, Taiwan.
Lab Chip. 2011 Feb 21;11(4):733-7. doi: 10.1039/c0lc00415d. Epub 2010 Dec 6.
This paper presents a magnetically driven valve via a permanent magnet pressing a spacer against deformable polydimethylsiloxane (PDMS) to fully close a microchannel. Its ability for electrical isolation, time response, and resistance to backpressure are interrogated. Simulation of the valve closing process was commenced along with experimental verification. Effects of PDMS thickness, and dimension and aspect ratio of microchannels were characterized. Up to 10 GΩ electrical isolation was demonstrated, as well as 50-70 ms valve response and ∼200 kPa resistible pressure. On-demand actuation for arbitrary flow patterns further quantifies its utility. With advantages of simple fabrication, flexible valving location, and no external power requirement, the on/off valve could be leveraged for proof-of-concept microfluidic devices and other applications.
本文提出了一种通过永磁体将垫圈压在可变形的聚二甲基硅氧烷（PDMS）上来完全关闭微通道的磁驱动阀。研究了其电隔离、响应时间和抗背压能力。对阀的关闭过程进行了模拟，并进行了实验验证。分析了 PDMS 厚度、微通道的尺寸和纵横比的影响。实验结果表明，该阀可实现高达 10 GΩ 的电隔离，50-70 ms 的阀响应时间和可抵抗约 200 kPa 的压力。按需控制任意流动模式进一步量化了其应用。由于其具有制造简单、灵活的阀位和无需外部电源等优点，该开关阀可用于概念验证微流控器件和其他应用。
