Mnif Leila, Mzid Amin, Amouri Ali, Chtourou Lassaad, Tahri Nabil
Department of Gastroenterology, Hedi Chaker University Hospital, and Université Sfax, Sfax, Tunisia.
Tunis Med. 2010 Dec;88(12):933-6.
Inflammatory bowel disease (IBD) impairs healthrelated quality of life (HRQOL).
To describe HRQOL in Tunisian patients with IBD and to compare it with a reference population.
HRQOL was assessed with the Tunisian versions of the Medical Outcomes Study Short Form 36 (SF 36) and the Inflammatory Bowel Disease Questionnaire (IBDQ-32).
Sixty two IBD patients were included (23 CD, 39 UC). The control group consisted of 62 healthy subjects. We have shown that HRQOL in Tunisian patients with IBD, measured with the SF-36, is lower than that of a Tunisian reference population without significant differences. Using the IBDQ-32, we found lower scores in women, in patients with CD, with material deprivation, and with active disease. Factors such as the experience of previous relapses or hospitalisations, disease duration, previous resective surgery, remission duration, maintenance therapy, marital status and smoking status do not have a significant impact on HRQOL in these patients.
Most patients with established inflammatory bowel disease showed only minor impairment of their HRQOL. However, women and the patients suffering from active and Crohn's disease as well as the materially deprived patients are most at risk.. Better clinical care and psychological counselling for these more vulnerable groups may improve their quality of life.
炎症性肠病（IBD）会损害健康相关生活质量（HRQOL）。
描述突尼斯IBD患者的HRQOL，并与参照人群进行比较。
使用突尼斯版的医学结局研究简明健康调查问卷（SF-36）和炎症性肠病问卷（IBDQ-32）对HRQOL进行评估。
纳入62例IBD患者（23例克罗恩病，39例溃疡性结肠炎）。对照组由62名健康受试者组成。我们发现，用SF-36测量的突尼斯IBD患者的HRQOL低于突尼斯参照人群，但无显著差异。使用IBDQ-32，我们发现女性、克罗恩病患者、物质匮乏患者以及疾病活动期患者的得分较低。既往复发或住院经历、病程、既往切除手术、缓解期时长、维持治疗、婚姻状况和吸烟状况等因素对这些患者的HRQOL没有显著影响。
大多数确诊的炎症性肠病患者的HRQOL仅受到轻微损害。然而，女性、患有活动性疾病和克罗恩病的患者以及物质匮乏的患者风险最高。为这些更脆弱的群体提供更好的临床护理和心理咨询可能会改善他们的生活质量。
