Sun Zhi-Guo, Miao Xiao-Gang, Yuan Hong, Zhao Xi-Bin, Wang Hao, Sun Jun-Gang
Department of the First Orthopaedics, People's Hospital of Xinjiang of Uygur Autonomous Region, Wulumuqi 830001, Xinjiang, China.
Zhongguo Gu Shang. 2010 Oct;23(10):734-8.
To investigate the clinical effects and safety of vertebroplasty and kyphoplasty for the senile osteoporotic vertebral compression fractures.
From December 2004 to June 2008, 28 patients (40 vertebrae) with osteoporotic vertebral compression fractures were treated with percutaneous vertebroplasty (PVP group), there were 11 males (14 vertebrae) and 17 females (26 vertebrae), with an average age of 72 years (ranged, 70 to 91 years). The fracture site of vertebral body was from T5 to L5. Other 31 patients (43 vertebrae) were treated with percutaneous kyphoplasty (PKP group), there were 13 males (18 vertebrae) and 18 females (25 vertebrae), with an average age of 74 years (ranged, 70 to 92 years). The fracture site of vertebral body was from T4 to L5. Theapeutic effects of all the patients were observed after operation, the item included visual analog scale (VAS), Oswestry score, Cobb angle, the height of anterior and middle column vertebra, and the incidence of cement leakage.
There was significant decrease in VAS score and Oswestry score after operation in both groups, there was significant difference between preoperative and postoperative (P < 0.01). There was no significant difference in VAS score and Oswestry score between two groups (P > 0.05). There was no significant difference in Cobb angles and the height of anterior and middle column vertebra between two groups before and after operation (P > 0.05). Among them, there were 3 vertebrae cement leakage in PVP group (7.5%) and 2 in PKP group (4.7%), but no clinical sympton occurred. There was no significant difference in the incidence of cement leakage between two groups (P > 0.05).
Vertebroplasty and kyphoplasty are safe and effective methods in treating senile osteoporotic vertebral compression fractures, which can restore the height of fractured vertebra, relieve pain and improve function as well as minimize the incidence of cement leakage.
探讨椎体成形术和后凸成形术治疗老年骨质疏松性椎体压缩骨折的临床疗效及安全性。
2004年12月至2008年6月，28例（40个椎体）骨质疏松性椎体压缩骨折患者接受经皮椎体成形术（PVP组），其中男性11例（14个椎体），女性17例（26个椎体），平均年龄72岁（范围70至91岁）。椎体骨折部位为T5至L5。另外31例（43个椎体）患者接受经皮后凸成形术（PKP组），其中男性13例（18个椎体），女性18例（25个椎体），平均年龄74岁（范围70至92岁）。椎体骨折部位为T4至L5。术后观察所有患者的治疗效果，观察项目包括视觉模拟评分（VAS）、Oswestry评分 Cobb角、椎体前中柱高度及骨水泥渗漏发生率。
两组术后VAS评分和Oswestry评分均显著降低，术前与术后比较差异有统计学意义（P<0.01）。两组VAS评分和Oswestry评分比较差异无统计学意义（P>0.05）。两组手术前后Cobb角及椎体前中柱高度比较差异无统计学意义（P>0.05）。其中，PVP组有3个椎体发生骨水泥渗漏（7.5%），PKP组有2个椎体发生骨水泥渗漏（4.7%），但均未出现临床症状。两组骨水泥渗漏发生率比较差异无统计学意义（P>0.05）。
椎体成形术和后凸成形术是治疗老年骨质疏松性椎体压缩骨折安全有效的方法，可恢复骨折椎体高度、缓解疼痛、改善功能并降低骨水泥渗漏发生率。
