Zahid Mohammad, Asif Naiyer, Sabir Aamir Bin, Siddiqui Yasir Salam, Julfiqar Mohammad
Department of Orthopaedic Surgery, Jawaharlal Nehru Medical College Hospital A.M.U. Aligarh, India.
Acta Orthop Belg. 2010 Oct;76(5):694-8.
Giant Cell tumour (GCT) or Osteoclastoma is a benign locally aggressive tumour with a tendency for local recurrence. Long tubular bones (75-90%) are frequent sites of involvement. GCT constitutes 5% of all primary bone tumours. Metachronous multicentric giant cell tumour of bone is a rare entity. Multicentric GCT, in contrast to unifocal GCT, has a tendency to involve the small bones of hands and feet, involving the metaphysis/diaphysis of long bones and tends to occur in a slightly younger population. We report a young girl presenting with metachronous multicentric recurrent benign GCT, with the lesions involving the ipsilateral right hand and distal humerus. She was successfully treated with an aggressive surgical approach (en-bloc resection).
骨巨细胞瘤(GCT)或破骨细胞瘤是一种具有局部复发倾向的良性局部侵袭性肿瘤。长管状骨(75 - 90%)是常见的受累部位。骨巨细胞瘤占所有原发性骨肿瘤的5%。异时性多中心骨巨细胞瘤是一种罕见的疾病。与单灶性骨巨细胞瘤相比,多中心骨巨细胞瘤倾向于累及手和脚的小骨,累及长骨的干骺端/骨干,且往往发生在年龄稍小的人群中。我们报告了一名年轻女孩,患有异时性多中心复发性良性骨巨细胞瘤,病变累及同侧右手和肱骨远端。她通过积极的手术方法(整块切除)得到了成功治疗。