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一名骨骼未成熟女孩上肢的异时性多中心巨细胞瘤:一种罕见的表现。

Metachronous multicentric giant cell tumour of the upper extremity in a skeletally immature girl : A rare presentation.

作者信息

Zahid Mohammad, Asif Naiyer, Sabir Aamir Bin, Siddiqui Yasir Salam, Julfiqar Mohammad

机构信息

Department of Orthopaedic Surgery, Jawaharlal Nehru Medical College Hospital A.M.U. Aligarh, India.

出版信息

Acta Orthop Belg. 2010 Oct;76(5):694-8.

Abstract

Giant Cell tumour (GCT) or Osteoclastoma is a benign locally aggressive tumour with a tendency for local recurrence. Long tubular bones (75-90%) are frequent sites of involvement. GCT constitutes 5% of all primary bone tumours. Metachronous multicentric giant cell tumour of bone is a rare entity. Multicentric GCT, in contrast to unifocal GCT, has a tendency to involve the small bones of hands and feet, involving the metaphysis/diaphysis of long bones and tends to occur in a slightly younger population. We report a young girl presenting with metachronous multicentric recurrent benign GCT, with the lesions involving the ipsilateral right hand and distal humerus. She was successfully treated with an aggressive surgical approach (en-bloc resection).

摘要

骨巨细胞瘤(GCT)或破骨细胞瘤是一种具有局部复发倾向的良性局部侵袭性肿瘤。长管状骨(75 - 90%)是常见的受累部位。骨巨细胞瘤占所有原发性骨肿瘤的5%。异时性多中心骨巨细胞瘤是一种罕见的疾病。与单灶性骨巨细胞瘤相比,多中心骨巨细胞瘤倾向于累及手和脚的小骨,累及长骨的干骺端/骨干,且往往发生在年龄稍小的人群中。我们报告了一名年轻女孩,患有异时性多中心复发性良性骨巨细胞瘤,病变累及同侧右手和肱骨远端。她通过积极的手术方法(整块切除)得到了成功治疗。

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