Corbeto E L, Lugo R, Martró E, Falguera G, Ros R, Avecilla A, Coll C, Saludes V, Casabona J
Center for Epidemiological Studies on HIV/AIDS & STI of Catalonia, ICO/Health Department, Generalitat de Catalunya, Badalona, Spain.
Int J STD AIDS. 2010 Oct;21(10):718-22. doi: 10.1258/ijsa.2010.010223.
We determined the prevalence of Chlamydia trachomatis (CT) infection and risk factors for its acquisition by women aged less than 35 years who were attending sexual health centres in the province of Barcelona in 2007. A convenience sample of 397 adolescents and young adult women aged between 16 and 35 years, stratified by age and recruitment site, were tested using realtime polymerase chain reaction by CT DNA. A standardized questionnaire was used to collect epidemiological and behavioural data on the participants, which were analysed in a multivariate logistic regression model. The overall prevalence of CT was 4%, significantly higher in those under 25 years of age (5.8% versus 1.6% over 25). The independent risk factors for CT infection were: foreign origin (odds ratio [OR] 4.7; confidence interval [CI] 1.02-21.8), having had a sexual partner in the last three months (OR 4.59; CI 1.16-18.08) and tobacco use the last 12 months (OR 6.38; CI 1.16-34.93). In conclusion, this is the first study performed in Catalonia showing a high prevalence of CT in young women, consistent with trends in the rest of Europe. Systematic monitoring of CT infection in sentinel populations such as this will inform future targeted screening programmes in our setting.
我们确定了2007年在巴塞罗那省性健康中心就诊的35岁以下女性沙眼衣原体（CT）感染的患病率及其感染的危险因素。通过实时聚合酶链反应检测CT DNA，对397名年龄在16至35岁之间、按年龄和招募地点分层的青少年及年轻成年女性进行了便利抽样检测。使用标准化问卷收集参与者的流行病学和行为数据，并在多变量逻辑回归模型中进行分析。CT的总体患病率为4%，25岁以下人群的患病率显著更高（5.8%对25岁以上人群的1.6%）。CT感染的独立危险因素为：外国裔（比值比[OR]4.7；置信区间[CI]1.02 - 21.8）、在过去三个月内有性伴侣（OR 4.59；CI 1.16 - 18.08）以及在过去12个月内吸烟（OR 6.38；CI 1.16 - 34.93）。总之，这是在加泰罗尼亚进行的第一项研究，显示年轻女性中CT的患病率较高，与欧洲其他地区的趋势一致。对这类哨点人群进行CT感染的系统监测将为我们地区未来的针对性筛查计划提供依据。
