Aggarwal Aditya N, Jain Anil K, Kumar Sudhir, Dhammi Ish K, Prashad Bhagwat
Department of Orthopedics, University College of Medical Sciences and GTB Hospital, Shahadara, Delhi - 110 095, India.
Indian J Orthop. 2007 Apr;41(2):129-33. doi: 10.4103/0019-5413.32044.
Segmental resection of bone in Giant Cell Tumor (GCT) around the knee, in indicated cases, leaves a gap which requires a complex reconstructive procedure. The present study analyzes various reconstructive procedures in terms of morbidity and various complications encountered.
Thirteen cases (M-six and F-seven; lower end femur-six and upper end tibia -seven) of GCT around the knee, radiologically either Campanacci Grade II, Grade II with pathological fracture or Grade III were included. Mean age was 25.6 years (range 19-30 years). Resection arthrodesis with telescoping (shortening) over intramedullary nail (n=5), resection arthrodesis with an intercalary allograft threaded over a long intramedullary nail (n=3) and resection arthrodesis with intercalary fibular autograft and simultaneous limb lengthening (n=5) were the procedure performed.
Shortening was the major problem following resection arthrodesis with telescoping (shortening) over intramedullary nail. Only two patients agreed for subsequent limb lengthening. The rest continued to walk with shortening. Infection was the major problem in all cases of resection arthrodesis with an intercalary allograft threaded over a long intramedullary nail and required multiple drainage procedures. Fusion was achieved after two years in two patients. In the third patient the allograft sequestrated. The patient underwent sequestrectomy, telescoping of fragments and ilizarov fixator application with subsequent limb lengthening. The patient was finally given an ischial weight relieving orthosis, 54 months after the index procedure. After resection arthrodesis with intercalary autograft and simultaneous lengthening the resultant gap (∼15cm) was partially bridged by intercalary nonvascularized dual fibular strut graft (6-7cm) and additional corticocancellous bone graft from ipsilateral patella. Simultaneous limb lengthening with a distal tibial corticotomy was performed on an ilizarov fixator. The complications were superficial infection (n=5), stress fracture of fibula (n=2). The stress fracture fibula required DCP fixation and bone grafting. The usual time taken for union and limb length equalization was approximately one year.
Resection arthrodesis with intercalary dual fibular autograft and cortico-cancellous bone grafting with simultaneous limb lengthening achieved limb length equalization with relatively short morbidity.
对于膝关节周围骨巨细胞瘤(GCT),在合适的病例中进行节段性骨切除会留下骨缺损,这需要复杂的重建手术。本研究分析了各种重建手术的发病率及所遇到的各种并发症。
纳入13例膝关节周围GCT患者(男性6例,女性7例;股骨下端6例,胫骨上端7例),放射学表现为坎帕纳奇II级、II级合并病理性骨折或III级。平均年龄25.6岁(范围19 - 30岁)。手术方式包括:髓内钉 telescoping(缩短)切除关节固定术(n = 5)、长髓内钉套入嵌入式同种异体骨切除关节固定术(n = 3)以及嵌入式腓骨自体骨移植并同期肢体延长切除关节固定术(n = 5)。
髓内钉 telescoping(缩短)切除关节固定术后主要问题是肢体缩短。只有2例患者同意后续肢体延长。其余患者继续带着肢体缩短行走。长髓内钉套入嵌入式同种异体骨切除关节固定术的所有病例中主要问题是感染,需要多次引流。2例患者在两年后实现融合。第3例患者同种异体骨发生骨坏死。该患者接受了死骨切除术、碎骨片 telescoping以及应用伊里扎洛夫固定器并随后进行肢体延长。在初次手术54个月后,最终给该患者佩戴了坐骨减压矫形器。嵌入式自体骨移植并同期延长切除关节固定术后,所形成的骨缺损(约15cm)部分由嵌入式非血管化双腓骨支撑移植骨(6 - 7cm)以及同侧髌骨的额外皮质松质骨移植骨桥接。在伊里扎洛夫固定器上进行胫骨远端皮质切开同期肢体延长。并发症包括表浅感染(n = 5)、腓骨应力性骨折(n = 2)。腓骨应力性骨折需要动力加压钢板固定和植骨。愈合及肢体长度均衡通常所需时间约为一年。
嵌入式双腓骨自体骨移植并皮质松质骨移植同时肢体延长的切除关节固定术实现了肢体长度均衡,且发病率相对较低。