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经椎弓根椎体增强器治疗爆裂骨折的长期疗效

Long-term results of transpedicle body augmenter in treating burst fractures.

作者信息

Li Allen, Chen Jung-Kuei, Li Kung-Chia, Hsieh Ching-Hsiang

机构信息

Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.

出版信息

Indian J Orthop. 2007 Oct;41(4):362-7. doi: 10.4103/0019-5413.37001.

Abstract

BACKGROUND

Short-segment fixation alone to treat thoracolumbar burst fractures is common but it has a 20-50% incidence of implant failure and rekyphosis. A transpedicle body augmenter (TpBA) to reinforce the vertebral body via posterior approach has been reported to prevent implant failure and increase the clinical success rate in treating burst fracture. This article is to evaluate the longterm results of short-segment fixation with TpBA for treatment of thoracolumbar burst fractures.

MATERIALS AND METHODS

Patients included in the study had a single-level burst fracture involving T11-L2 and no distraction or rotation element with limited neurological deficit. Patients in the control group (n = 42) were treated with short-segment posterior instrumentation alone, whereas patients in the augmented group (n = 90) were treated with a titanium spacer designed for transpedicle body reconstruction. The followup was 48-101 months. The radiographic and clinical results were evaluated and compared by Student's t test and Fisher's exact test.

RESULTS

The blood loss, operation time and hospitalization were similar in both the groups. The immediate postoperative anterior vertebral restoration rate of the augmented group was similar to that of the control group (97.6% ± 2.4% vs. 96.6% ± 3.2%). The final anterior vertebral restoration was greater in the augmented group than in the control group (93.3% ± 3.4% vs. 62.5% ± 11.2%). Immediate postoperative kyphotic angles were not significantly different between the groups (3.0° ± 1.8° vs. 5.1° ± 2.3°). The final kyphotic angles were less in the augmented group than the control group (7.3° ± 3.5° vs. 20.1° ± 5.4°). The augmented group had less (P < 0.001) implant failure [0% (n=0) vs. 23.8% (n=10)] for the control group) and more patients (P < 0.001) with no pain or minimal or occasional pain (Grade P1 or P2) than the control group [90.0% (n=81) vs. 66.7% (n=28)]. All patients in the augmented group and 39 (92.8%) patients in the control group experienced neurological recovery to Frankel Grade E. Three patients in the control group had improvement to Frankel Grade D from Frankel Grade C, but later had deterioration to Frankel Grade C because of loosening and dislodgement of the implant.

CONCLUSION

Posterior body reconstruction with TpBA can maintain kyphosis correction and vertebral restoration, prevent implant failure and lead to better clinical results.

摘要

背景

单纯采用短节段固定治疗胸腰椎爆裂骨折很常见,但植入物失败和后凸畸形复发率为20% - 50%。据报道,经椎弓根椎体增强器(TpBA)通过后路途径强化椎体可预防植入物失败,并提高爆裂骨折治疗的临床成功率。本文旨在评估采用TpBA短节段固定治疗胸腰椎爆裂骨折的长期疗效。

材料与方法

纳入研究的患者为单一节段T11 - L2爆裂骨折,无牵张或旋转因素,神经功能缺损有限。对照组(n = 42)患者仅接受短节段后路内固定治疗,而增强组(n = 90)患者采用专为经椎弓根椎体重建设计的钛制间隔器治疗。随访时间为48 - 101个月。通过学生t检验和Fisher精确检验评估并比较影像学和临床结果。

结果

两组患者的失血量、手术时间和住院时间相似。增强组术后即刻椎体前缘恢复率与对照组相似(97.6% ± 2.4% 对 96.6% ± 3.2%)。增强组最终椎体前缘恢复情况优于对照组(93.3% ± 3.4% 对 62.5% ± 11.2%)。两组术后即刻后凸角无显著差异(3.0° ± 1.8° 对 5.1° ± 2.3°)。增强组最终后凸角小于对照组(7.3° ± 3.5° 对 20.1° ± 5.4°)。增强组植入物失败率低于对照组(P < 0.001)[0%(n = 0)对23.8%(n = 10)],且无疼痛或轻微或偶尔疼痛(P1或P2级)的患者多于对照组(P < 0.001)[90.0%(n = 81)对66.7%(n = 28)]。增强组所有患者及对照组39例(92.8%)患者神经功能恢复至Frankel E级。对照组3例患者从Frankel C级改善至Frankel D级,但后来因植入物松动和移位又恶化至Frankel C级。

结论

采用TpBA进行椎体后重建可维持后凸畸形矫正和椎体恢复,预防植入物失败,并带来更好的临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3808/2989517/23bd29af3b39/IJOrtho-41-362-g001.jpg

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