Poggi Guido, Villani Laura, Bernardo Giovanni
Department of Oncology.
Rare Tumors. 2009 Jul 22;1(1):e6. doi: 10.4081/rt.2009.e6.
Glucagonomas are pancreatic islet cell tumors arising from the alpha cells which belong to neuroendocrine tumors. They frequently metastasize to the liver. We report the case of a 52- year old man with a pancreatic glucagonoma with synchronous multiple liver metastases treated by surgery, transarterial chemoembolization, percutaneous radiofrequency thermal ablation and long-acting octreotide. Our report confirms that a multimodal approach is very effective in patients with unresectable liver metastases from pancreatic endocrine tumors providing long-lasting palliation and probably prolonging survival.
胰高血糖素瘤是起源于α细胞的胰岛细胞瘤，属于神经内分泌肿瘤。它们常转移至肝脏。我们报告了一例52岁男性胰腺高血糖素瘤伴同步多发肝转移的病例，该患者接受了手术、经动脉化疗栓塞、经皮射频热消融及长效奥曲肽治疗。我们的报告证实，多模式治疗方法对患有不可切除的胰腺内分泌肿瘤肝转移患者非常有效，可提供持久的姑息治疗并可能延长生存期。
