Al-Faouri Ashraf, Ajarma Khaled, Alghazawi Samer, Al-Rawabdeh Sura, Zayadeen Adnan
Department of General Surgery, King Hussein Medical Center, Amman 11831, Jordan.
Department of Pathology, King Hussein Medical Center, Amman 11831, Jordan.
Case Rep Surg. 2016;2016:1484089. doi: 10.1155/2016/1484089. Epub 2016 Feb 14.
The rarity of glucagonoma imposes a challenge with most patients being diagnosed after a long period of treatment for their skin rash (months-years). Awareness of physicians and dermatologists of the characteristic necrolytic migratory erythema often leads to early diagnosis. Early diagnosis of glucagonoma even in the presence of resectable liver metastases may allow curative resection. Herein, we present a typical case of glucagonoma treated at our center and review the literature pertinent to its management.
胰高血糖素瘤极为罕见,这给诊断带来了挑战,大多数患者在出现皮疹后经过长时间(数月至数年)治疗才得以确诊。内科医生和皮肤科医生若能意识到特征性的坏死性游走性红斑,往往可实现早期诊断。即便存在可切除的肝转移灶,早期诊断胰高血糖素瘤仍有可能进行根治性切除。在此,我们呈现我院中心治疗的一例典型胰高血糖素瘤病例,并回顾其治疗相关的文献。