Jia Jun, Ren Jun, Gu Jin, Di Lijun, Song Guohong
Department of Medical Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University School of Oncology;
Rare Tumors. 2010 Sep 30;2(3):e44. doi: 10.4081/rt.2010.e44.
Sarcomatoid carcinoma is an extremely rare biphasic tumor characterized by a combination of malignant epithelial and mesenchymal cells. Limited data on sarcomatoid carcinoma showed that most cases occurred with advanced local disease and metastasis, and paraneoplastic syndromes were rare. We present the case of a 63-year-old man with lung sarcomatoid carcinoma associated with jejunum metastasis and leukocytosis, and its clinical, macroscopic, and histopathological features. This case emphasizes the importance of recognizing paraneoplastic syndromes and metastasis of sarcomatoid carcinoma at diagnosis.
肉瘤样癌是一种极其罕见的双相肿瘤,其特征是恶性上皮细胞和间充质细胞同时存在。关于肉瘤样癌的有限数据表明,大多数病例发生时伴有局部晚期疾病和转移,副肿瘤综合征罕见。我们报告一例63岁男性肺肉瘤样癌合并空肠转移和白细胞增多症的病例,以及其临床、大体和组织病理学特征。该病例强调了在诊断时认识肉瘤样癌副肿瘤综合征和转移的重要性。