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[细胞黄素在乳腺癌多药化疗中的应用]

[Cytoflavin in polychemotherapy of breast cancer].

作者信息

Kashuro V A, Glushkov S I, Zheregelia S N

出版信息

Antibiot Khimioter. 2010;55(7-8):30-3.

Abstract

The efficacy of cytoflavin as a supporting drug in the CAF chemotherapy of breast cancer was studied. It was estimated by the tolerability, the peripheric blood index dynamics, the patients general condition (Karnovsky Index) and the frequency of the side effects. For the immediate estimation of the polychemotherapy and cytoflavin effects on the cytoprotection natural system state, the dynamics of the glutathione metabolism and the lipid peroxidation in the erythrocytes was investigated.

摘要

研究了细胞黄素作为辅助药物在乳腺癌CAF化疗中的疗效。通过耐受性、外周血指标动态变化、患者一般状况(卡诺夫斯基指数)和副作用发生频率进行评估。为了直接评估多药化疗和细胞黄素对细胞保护自然系统状态的影响,研究了红细胞中谷胱甘肽代谢和脂质过氧化的动态变化。

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