Bloom Jason D, Bleier Benjamin S, Mirza Natasha, Chalian Ara A, Thaler Erica R
Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Ann Otol Rhinol Laryngol. 2010 Nov;119(11):736-41.
The objectives of this study were 1) to understand which anatomic variables are associated with failed endoscopic exposure of Zenker's diverticulum and 2) to enable preoperative selection of patients suitable for endoscopic repair of Zenker's diverticulum on the basis of anatomic variables.
We performed a prospective, Institutional Review Board-approved study of 30 patients undergoing attempted endoscopic repair of Zenker's diverticulum. Three categorical variables (sex, presence of maxillary dentition, and Mallampati score) and 6 continuous variables (age, neck circumference, hyomental distance, neck length, neck extension, and body mass index [BMI]) were collected before operation and then correlated to successful endoscopic exposure of the Zenker's pouch by use of a Fisher's exact test and Student's t-test, respectively.
Exposure was unsuccessful in 9 of 30 patients (30%). Factors that correlated significantly with exposure failure included a shorter neck length (7.2 +/- 1.2 cm; p = 0.047), a shorter hyomental distance (5.0 +/- 1.1 cm; p = 0.004), and a higher BMI (27.2 +/- 4.0 kg/m2; p = 0.05). The presence of maxillary dentition did not reach significance in exposure failure, but did show a trend toward an association.
Surgical exposure in endoscopic repair of Zenker's diverticulum tends to be significantly less successful in patients with short necks, decreased hyomental distance, and/or a high BMI. An open approach should be considered in this patient population.
本研究的目的是1)了解哪些解剖学变量与Zenker憩室内镜暴露失败相关,以及2)能够根据解剖学变量对适合Zenker憩室内镜修复的患者进行术前选择。
我们对30例尝试进行Zenker憩室内镜修复的患者进行了一项前瞻性、经机构审查委员会批准的研究。在手术前收集了三个分类变量(性别、上颌牙列情况和Mallampati评分)和六个连续变量(年龄、颈围、颏下距离、颈部长度、颈部伸展度和体重指数[BMI]),然后分别使用Fisher精确检验和Student t检验将它们与Zenker憩室的成功内镜暴露相关联。
30例患者中有9例(30%)暴露失败。与暴露失败显著相关的因素包括较短的颈部长度(7.2±1.2厘米;p = 0.047)、较短的颏下距离(5.0±1.1厘米;p = 0.004)和较高的BMI(27.2±4.0千克/平方米;p = 0.05)。上颌牙列的存在在暴露失败方面未达到显著水平,但确实显示出一种关联趋势。
对于颈部短、颏下距离减小和/或BMI高的患者,Zenker憩室内镜修复中的手术暴露往往明显不太成功。对于这一患者群体应考虑采用开放手术方法。