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生物补片加强的脐疝修补术

Umbilical herniorrhaphy reinforced with biologic mesh.

作者信息

Edelman David S, Bellows Charles F

机构信息

Department of Surgery, Doctor's Hospital, 6401 SW 87th Avenue, Suite 205, Miami, FL 33173, USA.

出版信息

Am Surg. 2010 Nov;76(11):1205-9.

Abstract

The true recurrence rate after umbilical hernia repair in not known. After simple closure, the reported rate of recurrence in the literature is as high as 54 per cent. With synthetic mesh repair, the recurrence rates are lowered to less than 10 per cent. However, synthetic mesh is associated with complications such as enterocutaneous fistula and mesh infections. This preliminary study looks at the safety and effectiveness of biologic extracellular matrix mesh reinforcement in the repair of umbilical hernias. We retrospectively reviewed all patients who underwent repair of an umbilical hernia defect (2-3 cm) with primary approximation of the margins and reinforced using a biologic mesh placed beneath the umbilical fascia from 2007 to 2009. Demographic data were collected. Patients were followed prospectively at 2 weeks, 8 weeks, 6 months, and 1 year. Data were reviewed for postoperative complications, hernia recurrence, and patient satisfaction. During the study period, 16 patients completed the 1 year follow-up. There were 10 men and six women. Ages ranged from 28 to 75 years with a mean age of 47.6 years. The hernias were 2 to 3 cm in size. Complications were minimal. Overall patient satisfaction with the procedure was high. There were no mesh infections. During a mean follow-up of 12 months, only one patient had recurrent hernia (6%). This preliminary evaluation shows promise for an alternative treatment of umbilical hernias using biologic extracellular matrix mesh added as an underlay to reinforce a primary closure. The biologic mesh has a low incidence of infection and complications and results in high patient satisfaction. This preliminary study begs for a randomized, prospective evaluation with long-term follow-up.

摘要

脐疝修补术后的真实复发率尚不清楚。单纯缝合后,文献报道的复发率高达54%。使用合成补片修补时,复发率可降至10%以下。然而,合成补片会引发诸如肠皮肤瘘和补片感染等并发症。这项初步研究探讨了生物细胞外基质补片加强修补脐疝的安全性和有效性。我们回顾性分析了2007年至2009年期间所有接受脐疝缺损(2 - 3厘米)修补术的患者,手术采用边缘一期缝合,并在脐筋膜下放置生物补片进行加强。收集了人口统计学数据。对患者进行前瞻性随访,随访时间点为术后2周、8周、6个月和1年。审查了术后并发症、疝复发情况以及患者满意度的数据。在研究期间,16例患者完成了1年的随访。其中男性10例,女性6例。年龄范围为28至75岁,平均年龄为47.6岁。疝大小为2至3厘米。并发症极少。总体而言,患者对该手术的满意度较高。未发生补片感染。在平均12个月的随访期间,只有1例患者出现复发性疝(6%)。这项初步评估表明,使用生物细胞外基质补片作为底层加强一期缝合来治疗脐疝是一种有前景的替代方法。生物补片感染和并发症的发生率较低,患者满意度较高。这项初步研究需要进行随机、前瞻性评估并长期随访。

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