Pata Giacomo, Casella Claudio, Benvenuti Mauro, Crea Nicola, Di Betta Ernesto, Salerni Bruno
Department of Medical & Surgical Sciences, 1st Division of General Surgery, University of Brescia, Brescia, Italy.
Am Surg. 2010 Nov;76(11):1240-3.
Mediastinal goiter (MG) removal occasionally needs sternotomy, mainly in case of subaortic extension. We aimed to test the hypothesis that sternal-split may safely replace full sternotomy for MG removal (through total thyroidectomy) when thoracic access is required. We conducted a prospective observational cohort study comparing 15 subaortic MGs receiving sternal-split with 87 MGs undergoing cervicotomy alone between January 1997 and June 2009. Among 15 cases requiring sternal incision, sternal-split was extended to the angle of Louis in nine patients (60%), to the third intercostal space (IS) in one of five (20%) cases of MGs with anterior mediastinum involvement, and in five of 10 (50%) cases with posterior involvement (P = 0.6). Full sternotomy was never necessary. The median hospitalization was 5 days (range, 4-8 days) after sternal access as compared with 3 days (range, 2-4 days) after cervicotomy (P = 0.04). Complications were similar in these two study groups: one postoperative bleeding in each group and three recurrent laryngeal nerve palsies after cervicotomy (P = 0.5). There was no operative mortality, blood transfusion, tracheotomy requirement, wound infection, or persistent hypoparathyroidism. Proper extension of sternal-split to the second or third IS allows an adequate approach to both the anterior and to the posterior mediastinum, thus permitting safe management of MGs requiring thoracic access.
纵隔甲状腺肿(MG)切除术偶尔需要进行胸骨切开术,主要用于主动脉弓下扩展的情况。我们旨在验证这样一个假设:当需要经胸入路时,胸骨劈开术可安全替代全胸骨切开术用于MG切除(通过全甲状腺切除术)。我们进行了一项前瞻性观察队列研究,比较了1997年1月至2009年6月期间接受胸骨劈开术的15例主动脉弓下MG患者和仅接受颈部切开术的87例MG患者。在15例需要胸骨切开的病例中,9例患者(60%)的胸骨劈开术延伸至胸骨角,1例累及前纵隔的MG患者(5例中的1例,20%)延伸至第三肋间间隙(IS),10例累及后纵隔的患者中有5例(50%)延伸至此(P = 0.6)。从未需要进行全胸骨切开术。胸骨入路后的中位住院时间为5天(范围4 - 8天),而颈部切开术后为3天(范围2 - 4天)(P = 0.04)。这两个研究组的并发症相似:每组各有1例术后出血,颈部切开术后有3例喉返神经麻痹(P = 0.5)。没有手术死亡、输血、气管切开需求、伤口感染或持续性甲状旁腺功能减退。将胸骨劈开术适当延伸至第二或第三肋间间隙可充分显露前纵隔和后纵隔,从而能够安全处理需要经胸入路的MG。