Gupta Y, Gupta M, Maheshwari R, Mittal T
Institute of Ophthalmology, Aligarh Muslim University B-6, Medical Colony, Aligarh-202002, (UP), India.
Nepal J Ophthalmol. 2009 Jul-Dec;1(2):123-8. doi: 10.3126/nepjoph.v1i2.3687.
to study the role of'Xerosis Meter' in screening of dry eye cases in a large population and compare its results with Schirmer's test and tear break-up time.
in a cross sectional study with a control group dry eye was evaluated with Xerosis Meter, Schirmer test and tear film break-up time (TBUT). Cases included in the study were divided into two groups. Group I (Control Group) comprised of asymptomatic patients while Group II (Test Group) had patients showing symptoms and signs of dry eye. The Group II was further divided into two subgroups. Group IIa had cases showing positive result with either of the two tests Schirmer test or TBUT. Group IIb had cases which showed positive results with Xerosis Meter but normal results with the other two tests.
all the observations were statistically analyzed using SPSS version 11.5 software. The results obtained were compared statistically using unpaired t-test and chi-square test. The p value of < 0.05 was considered as significant.
There was a statistically significant difference between the means of Xerosis Meter, Schirmer test and TBUT of the two groups: Group I and Group IIa (p value < 0.001). On comparing Group I and Group IIb the difference was found to be statistically significant with Xerosis Meter (p value <0.001). The sensitivity and specificity ofXerosis Meter were 85.7% and 80.2% respectively. This was higher than that of the Schirmer's test (81.3% and 74.9%) and TBUT (73.2% and 68.7%).
the "Xerosis Meter" is an effective alternate in screening of dry eye cases. It is more effective than the TBUT and as effective as the Schirmer's test in detecting both the normal and dry eye patients.
研究“干眼仪”在大规模人群中筛查干眼病例的作用,并将其结果与泪液分泌试验和泪膜破裂时间进行比较。
在一项设有对照组的横断面研究中,使用干眼仪、泪液分泌试验和泪膜破裂时间(TBUT)对干眼进行评估。纳入研究的病例分为两组。第一组(对照组)由无症状患者组成,而第二组(试验组)有表现出干眼症状和体征的患者。第二组进一步分为两个亚组。第二组a亚组的病例在泪液分泌试验或TBUT这两项检查中任一项呈阳性结果。第二组b亚组的病例干眼仪检查结果呈阳性,但其他两项检查结果正常。
所有观察结果均使用SPSS 11.5版软件进行统计学分析。所得结果采用成组t检验和卡方检验进行统计学比较。p值<0.05被认为具有统计学意义。
两组(第一组和第二组a亚组)的干眼仪、泪液分泌试验和TBUT平均值之间存在统计学显著差异(p值<0.001)。比较第一组和第二组b亚组时,发现干眼仪检查结果存在统计学显著差异(p值<0.001)。干眼仪的敏感性和特异性分别为85.7%和80.2%。这高于泪液分泌试验(81.3%和74.9%)和TBUT(73.2%和68.7%)。
“干眼仪”是筛查干眼病例的一种有效替代方法。在检测正常和干眼患者方面,它比TBUT更有效,与泪液分泌试验效果相当。