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一项比较使用三角形与矩形巩膜瓣进行小梁切除术效果的随机临床试验。

A randomised clinical trial comparing the outcome of trabeculectomy using triangular versus rectangular scleral flaps.

作者信息

Sharma A, Das H, Adhikari S, Lavaju P, Shrestha B G

机构信息

Department of Ophthalmology, B P Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal.

出版信息

Nepal J Ophthalmol. 2009 Jan-Jun;1(1):20-4. doi: 10.3126/nepjoph.v1i1.3669.

DOI:10.3126/nepjoph.v1i1.3669
PMID:21141017
Abstract

BACKGROUND

trabeculectomy is the standard surgical procedure for management of glaucoma.

OBJECTIVE

to compare the outcome of triangular and rectangular scleral flaps in trabeculectomy.

MATERIALS AND METHODS

this study was carried out in the Department ofOphthalmology, BPKIHS, Dharan, over a period of one year. A total of 22 patients undergoing trabeculectomy were randomized to undergo either trabeculectomy with triangular scleral flap (Group A= 11 eyes) or trabeculectomy with rectangular flap (Group B = 11 eyes).

OUTCOME MEASUREMENT

the parameters studied were intraocular pressure (IOP), anterior chamber depth (ACD), bleb characteristics and surgical complications.

STATISTICS

P value of<0.05 was considered significant. All calculations were executed using SPSS 11.0 software program.

RESULTS

the age ranged between 40 to 76 years with the mean of 56.5 +/- 9.25 years. The most common preoperative diagnosis was angle closure glaucoma. The postoperative percentage of IOP reduction (Group A=68.9%; Group B=66.51%) was statically significant in both the groups (p=0.001). Trabeculectomy was almost equally effective with complete surgical success of 91% in group A, and 82% in group B (p=0.534). Final bleb scores were almost similar in both the groups with 3.27 +/- 1.5 in group A and 3.36 +/- 1.21 in group B (p=0.877). Hypotony with the IOP less than 6 mmHg was found in the first post-operative day in 2 patients in Group A and in 1 in Group B. All of them improved spontaneously within a week.

CONCLUSION

both triangular and rectangular scleral flaps in trabeculectomy are equally effective in terms of post surgical IOP control, bleb characteristics and complications.

摘要

背景

小梁切除术是治疗青光眼的标准外科手术。

目的

比较小梁切除术中三角形巩膜瓣和矩形巩膜瓣的手术效果。

材料与方法

本研究在达兰BPKIHS眼科进行,为期一年。共有22例行小梁切除术的患者被随机分为两组,分别接受三角形巩膜瓣小梁切除术(A组=11只眼)或矩形巩膜瓣小梁切除术(B组=11只眼)。

观察指标

研究的参数包括眼压(IOP)、前房深度(ACD)、滤过泡特征和手术并发症。

统计学方法

P值<0.05被认为具有统计学意义。所有计算均使用SPSS 11.0软件程序执行。

结果

年龄范围为40至76岁,平均年龄为56.5±9.25岁。最常见的术前诊断为闭角型青光眼。两组术后眼压降低百分比(A组=68.9%;B组=66.51%)均具有统计学意义(p=0.001)。小梁切除术的效果几乎相同,A组手术完全成功率为91%,B组为82%(p=0.534)。两组最终滤过泡评分几乎相似,A组为3.27±1.5,B组为3.36±1.21(p=0.877)。术后第1天,A组有2例患者眼压低于6 mmHg,B组有1例。所有患者均在一周内自行恢复。

结论

小梁切除术中三角形巩膜瓣和矩形巩膜瓣在术后眼压控制、滤过泡特征和并发症方面同样有效。

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