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透析链对接受血液透析患者死亡率的影响。

The effect of dialysis chains on mortality among patients receiving hemodialysis.

机构信息

Medical Technology and Practice Patterns Institute, 4733 Bethesda Ave., Bethesda, MD 20814, USA.

出版信息

Health Serv Res. 2011 Jun;46(3):747-67. doi: 10.1111/j.1475-6773.2010.01219.x. Epub 2010 Dec 9.

Abstract

OBJECTIVE

To examine the association between dialysis facility chain affiliation and patient mortality.

STUDY SETTING

Medicare dialysis population.

STUDY DESIGN

Data from the United States Renal Data System (USRDS) were used to identify 3,601 free-standing dialysis facilities and 34,914 Medicare patients' incidence to end-stage renal disease (ESRD) in 2004. Mixed-effect regression models were used to estimate patient mortality by dialysis facility chain and profit status during the 2-year follow-up.

DATA COLLECTION

USRDS data were matched with facility, cost, and census data.

PRINCIPAL FINDINGS

Of the five largest dialysis chains, the lowest mortality risk was observed among patients dialyzed at nonprofit (NP) Chain 5 facilities. Compared with Chain 5, hazard ratios were 19 percent higher (95 percent CI 1.06-1.34) and 24 percent higher (95 percent CI 1.10-1.40) for patients dialyzed at for-profit (FP) Chain 1 and Chain 2 facilities, respectively. In addition, patients at FP facilities had a 13 percent higher risk of mortality than those in NP facilities (95 percent CI 1.06-1.22).

CONCLUSIONS

Large chain affiliation is an independent risk factor for ESRD mortality in the United States. Given the movement toward further consolidation of large FP chains, reasons behind the increase in mortality require scrutiny.

摘要

目的

研究透析机构连锁附属关系与患者死亡率之间的关联。

研究场所

医疗保险透析人群。

研究设计

利用美国肾脏数据系统(USRDS)的数据,于 2004 年确定了 3601 家独立透析机构和 34914 名医疗保险患者的终末期肾病(ESRD)发病情况。采用混合效应回归模型,在 2 年的随访期间,根据透析机构连锁和盈利状况来估计患者死亡率。

数据收集

USRDS 数据与机构、成本和人口普查数据相匹配。

主要发现

在五个最大的透析连锁中,非营利性(NP)连锁 5 的患者死亡率最低。与连锁 5 相比,在营利性(FP)连锁 1 和连锁 2 的患者中,风险比分别高出 19%(95%CI 1.06-1.34)和 24%(95%CI 1.10-1.40)。此外,FP 机构的患者死亡率比 NP 机构高 13%(95%CI 1.06-1.22)。

结论

大型连锁附属关系是美国 ESRD 死亡率的一个独立危险因素。鉴于大型 FP 连锁进一步整合的趋势,需要仔细审查死亡率上升的原因。

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