Mendes Eva, Herdeiro Maria Teresa, Pimentel Francisco
Secção Autónoma de Ciências da Saúde e Centro de Investigação em Tecnologias da Saúde, Universidade de Aveiro, Aveiro.
Acta Med Port. 2010 Sep-Oct;23(5):901-8. Epub 2010 Oct 22.
The use of herbal complementary and alternative medicines is growing among Portuguese cancer patients, contributing to a higher risk for unwanted interactions, especially due to the narrow therapeutic index of most oncolytic drugs. A literature review was carried out in order to determine which medicinal plants are most commonly used by cancer patients, in Europe and USA, and their risk of interaction with the multiple medications taken by those patients. The collected information reveals a high degree of herb-drug interaction suggesting that patients under antineoplastic treatments should avoid the concomitant use of herbal medicines. These findings show that it is extremely important to have a clear knowledge of the herbal complementary and alternative medicines used by Portuguese cancer patients and to assess healthcare professionals' familiarity and attitude towards its use by cancer patients.
在葡萄牙癌症患者中，草药补充剂和替代药物的使用正在增加，这导致了不必要相互作用的风险更高，尤其是因为大多数溶瘤药物的治疗指数较窄。为了确定欧洲和美国癌症患者最常用的药用植物及其与这些患者所服用多种药物相互作用的风险，进行了一项文献综述。收集到的信息显示草药与药物之间存在高度相互作用，这表明接受抗肿瘤治疗的患者应避免同时使用草药。这些发现表明，清楚了解葡萄牙癌症患者使用的草药补充剂和替代药物，以及评估医护人员对癌症患者使用这些药物的熟悉程度和态度极其重要。
