Department of Neurology, Keimyung University School of Medicine, Republic of Korea.
J Neurol Sci. 2011 Feb 15;301(1-2):93-5. doi: 10.1016/j.jns.2010.11.009. Epub 2010 Dec 13.
Although several papers have been published on perverted head shaking nystagmus (PHSN) associated with focal brainstem or cerebellar lesion, there are no reports of a focal pontine infarct that causes PHSN. We report a patient with focal pontine infarction who presented with sustained dizziness, limb dysmetria on the left extremity, decreased sensations to position and vibration of the left extremity, and gait imbalance. Only vestibular abnormality was downbeat nystagmus after vigorous head shakings. The maximum slow phase velocity of PHSN was 26°/s, and its duration was about 20s. This is the first report of PHSN associated with focal pontine infarction. Crossed ventral tegmental tract and velocity storage mechanism of vestibulocerebellum might be related on PHSN in this case.
尽管已有几篇关于与局灶性脑干或小脑病变相关的变态性摇头眼震（PHSN）的论文发表，但尚无报道表明局灶性脑桥梗死可引起 PHSN。我们报告了一例局灶性脑桥梗死患者，其表现为持续性头晕、左侧肢体运动障碍、左侧肢体位置觉和震动觉减退以及步态不平衡。仅在剧烈摇头后出现前庭异常的下跳性眼震。PHSN 的最大慢相速度为 26°/s，持续时间约为 20s。这是首例与局灶性脑桥梗死相关的 PHSN 报告。本例中，交叉腹侧被盖束和前庭小脑的速度储存机制可能与 PHSN 有关。
