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3423 例大学附属医院紧急气管插管:气道结果和并发症。

3,423 emergency tracheal intubations at a university hospital: airway outcomes and complications.

机构信息

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, USA.

出版信息

Anesthesiology. 2011 Jan;114(1):42-8. doi: 10.1097/ALN.0b013e318201c415.

Abstract

BACKGROUND

There are limited outcome data regarding emergent nonoperative intubation. The current study was undertaken with a large observational dataset to evaluate the incidence of difficult intubation and complication rates and to determine predictors of complications in this setting.

METHODS

Adult nonoperating room emergent intubations at our tertiary care institution from December 5, 2001 to July 6, 2009 were reviewed. Prospectively defined data points included time of day, location, attending physician presence, number of attempts, direct laryngoscopy view, adjuvant use, medications, and complications. At our institution, a senior resident with at least 24 months of anesthesia training is the first responder for all emergent airway requests. The primary outcome was a composite airway complication variable that included aspiration, esophageal intubation, dental injury, or pneumothorax.

RESULTS

A total of 3,423 emergent nonoperating room airway management cases were identified. The incidence of difficult intubation was 10.3%. Complications occurred in 4.2%: aspiration, 2.8%; esophageal intubation, 1.3%; dental injury, 0.2%; and pneumothorax, 0.1%. A bougie introducer was used in 12.4% of cases. Among 2,284 intubations performed by residents, independent predictors of the composite complication outcome were as follows: three or more intubation attempts (odds ratio, 6.7; 95% CI, 3.2-14.2), grade III or IV view (odds ratio, 1.9; 95% CI, 1.1-3.5), general care floor location (odds ratio, 1.9; 95% CI, 1.2-3.0), and emergency department location (odds ratio, 4.7; 95% CI, 1.1-20.4).

CONCLUSIONS

During emergent nonoperative intubation, specific clinical situations are associated with an increased risk of airway complication and may provide a starting point for allocation of experienced first responders.

摘要

背景

目前针对紧急非手术插管的结果数据有限。本研究采用大型观察性数据集,评估在这种情况下困难插管的发生率和并发症发生率,并确定并发症的预测因素。

方法

对 2001 年 12 月 5 日至 2009 年 7 月 6 日期间,我们的三级护理机构的非手术急诊插管进行了回顾性分析。前瞻性定义的数据点包括一天中的时间、地点、主治医生的存在、尝试次数、直接喉镜视图、辅助使用、药物和并发症。在我们的机构中,一名具有至少 24 个月麻醉培训经验的高级住院医师是所有紧急气道请求的第一反应者。主要结局是包括吸入、食管插管、牙齿损伤或气胸的复合气道并发症变量。

结果

共确定了 3423 例非手术急诊气道管理病例。困难插管的发生率为 10.3%。并发症发生率为 4.2%:吸入,2.8%;食管插管,1.3%;牙齿损伤,0.2%;气胸,0.1%。12.4%的病例使用了气管插管引导器。在 2284 例由住院医师进行的插管中,复合并发症结果的独立预测因素如下:三次或更多次插管尝试(比值比,6.7;95%可信区间,3.2-14.2)、III 级或 IV 级视图(比值比,1.9;95%可信区间,1.1-3.5)、普通护理病房位置(比值比,1.9;95%可信区间,1.2-3.0)和急诊科位置(比值比,4.7;95%可信区间,1.1-20.4)。

结论

在紧急非手术插管期间,特定的临床情况与气道并发症的风险增加相关,这可能为分配有经验的第一反应者提供起点。

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