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接受开颅手术的局灶性癫痫发作患者大脑的病理检查结果。

Pathologic findings in brains of patients with focal epileptic seizures who had a craniotomy procedure.

作者信息

Wee A S, Parent A D, Ashley R A

机构信息

Department of Neurology, University Medical Center, Jackson, MS.

出版信息

J Miss State Med Assoc. 1990 Jul;31(7):219-21.

PMID:2115086
Abstract

This report reviews the pathologic findings in brains of 12 patients with focal epileptic seizures who had a craniotomy procedure. A majority of patients (seven) had either a cerebral neoplasm or a developmental abnormality (tuberous sclerosis and hamartoma), and these were found in six of the nine patients with chronic and intractable seizures. Four patients had cortical gliosis or scarring, and one had a bacterial brain abscess. Ten patients had a visible focal structural lesion during cranial imaging procedures, and in two instances, the MRI study was more sensitive than the CT in detecting a cerebral lesion.

摘要

本报告回顾了12例行开颅手术的局灶性癫痫发作患者脑部的病理检查结果。大多数患者(7例)患有脑肿瘤或发育异常(结节性硬化症和错构瘤),在9例慢性顽固性癫痫发作患者中有6例发现此类情况。4例患者有皮质胶质增生或瘢痕形成,1例有细菌性脑脓肿。10例患者在头颅影像学检查中可见局灶性结构病变,有2例在检测脑部病变方面,MRI检查比CT更敏感。

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