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阿义马林试验期间出现加速性室性自主心律：一例报告

Accelerated idioventricular rhythm during ajmaline test: a case report.

作者信息

Sorgente Antonio, Yazaki Yoshinao, Capulzini Lucio, Sarkozy Andrea, de Asmundis Carlo, Chierchia Gian-Battista, Stephan-Andreas Mehmet, Brugada Pedro

机构信息

Heart Rhythm Management Center, UZ Brussel-VUB, Laarbeeklaan 101, 1090 Brussels (Belgium).

出版信息

Indian Pacing Electrophysiol J. 2010 Oct 31;10(10):474-8.

PMID:21151386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2974335/
Abstract

We present an unusual transient pro-arrhythmic effect of ajmaline in a patient with resuscitated cardiac arrest and a left ventricular apical aneurysm. We discuss the clinical presentation and the possible physio-pathological explanation for this new pro-arrhythmic effect linked to administration of intravenous ajmaline.

摘要

我们报告了一例复苏后心脏骤停且伴有左心室心尖部室壁瘤的患者使用阿义马林后出现的罕见短暂促心律失常效应。我们讨论了该临床表现以及与静脉注射阿义马林相关的这种新的促心律失常效应可能的生理病理机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4723/2974335/99e5a14be9e4/ipej100474-01C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4723/2974335/a348a96c6272/ipej100474-01A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4723/2974335/301d0f29300f/ipej100474-01B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4723/2974335/99e5a14be9e4/ipej100474-01C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4723/2974335/a348a96c6272/ipej100474-01A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4723/2974335/301d0f29300f/ipej100474-01B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4723/2974335/99e5a14be9e4/ipej100474-01C.jpg

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本文引用的文献

1
A prospective study on spontaneous fluctuations between diagnostic and non-diagnostic ECGs in Brugada syndrome: implications for correct phenotyping and risk stratification.一项关于Brugada综合征诊断性与非诊断性心电图自发波动的前瞻性研究：对正确表型分型和风险分层的意义。
Eur Heart J. 2006 Nov;27(21):2544-52. doi: 10.1093/eurheartj/ehl205. Epub 2006 Sep 4.
2
Electrocardiogram interpretation and class I blocker challenge in Brugada syndrome.Brugada综合征的心电图解读与I类阻滞剂激发试验
J Electrocardiol. 2006 Oct;39(4 Suppl):S115-8. doi: 10.1016/j.jelectrocard.2006.05.014. Epub 2006 Aug 28.
3
Accelerated idioventricular rhythm in the post-thrombolytic era: incidence, prognostic implications, and modulating mechanisms after direct percutaneous coronary intervention.
溶栓治疗时代后的加速性室性自主心律：直接经皮冠状动脉介入治疗后的发生率、预后意义及调节机制
Ann Noninvasive Electrocardiol. 2005 Apr;10(2):179-87. doi: 10.1111/j.1542-474X.2005.05624.x.
4
The ajmaline challenge in Brugada syndrome: diagnostic impact, safety, and recommended protocol.布鲁加达综合征中的阿义马林激发试验：诊断意义、安全性及推荐方案
Eur Heart J. 2003 Jun;24(12):1104-12. doi: 10.1016/s0195-668x(03)00195-7.
5
Usefulness of reperfusion ventricular arrhythmias in non-invasive prediction of early reperfusion and sustained coronary artery patency in acute myocardial infarction.再灌注性室性心律失常在急性心肌梗死早期再灌注及冠状动脉持续通畅无创预测中的作用
J Thromb Thrombolysis. 2001 Dec;12(3):231-6. doi: 10.1023/a:1015275008339.
6
'Localized' right ventricular morphological abnormalities in patients with the Brugada syndrome: what is their significance?布加综合征患者的“局限性”右心室形态异常：其意义何在？
Eur Heart J. 2001 Jun;22(12):982-4. doi: 10.1053/euhj.2000.2522.
7
Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts.钠通道阻滞剂可识别ST段抬高及右束支传导阻滞但心脏结构正常的患者发生猝死的风险。
Circulation. 2000 Feb 8;101(5):510-5. doi: 10.1161/01.cir.101.5.510.
8
Postrepolarization refractoriness versus conduction slowing caused by class I antiarrhythmic drugs: antiarrhythmic and proarrhythmic effects.I类抗心律失常药物引起的复极后不应期与传导减慢：抗心律失常作用和促心律失常作用
Circulation. 1998 Jun 30;97(25):2567-74. doi: 10.1161/01.cir.97.25.2567.
9
Death after ajmaline administration.阿义马林给药后死亡。
Am J Cardiol. 1980 Apr;45(4):905. doi: 10.1016/0002-9149(80)90139-3.
10
Reperfusion arrhythmia: a marker of restoration of antegrade flow during intracoronary thrombolysis for acute myocardial infarction.再灌注心律失常：急性心肌梗死冠状动脉内溶栓期间顺行血流恢复的一个标志。
Am Heart J. 1983 Jan;105(1):26-32. doi: 10.1016/0002-8703(83)90274-0.