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Genetic variation in the human brain dopamine system influences motor learning and its modulation by L-Dopa.人类大脑多巴胺系统的遗传变异影响运动学习及其对 L-DOPA 的调节。
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本文引用的文献

1
Dissociable effects of dopamine on neuronal firing rate and synchrony in the dorsal striatum.多巴胺对背侧纹状体神经元放电率和同步性的分离影响。
Front Integr Neurosci. 2009 Oct 30;3:28. doi: 10.3389/neuro.07.028.2009. eCollection 2009.
2
Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's disease.在帕金森病模型中，纹状体中等棘状神经元的反复侧支连接受到破坏。
J Neurosci. 2008 May 21;28(21):5504-12. doi: 10.1523/JNEUROSCI.5493-07.2008.
3
Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction.急性多巴胺依赖性运动功能障碍期间皮质纹状体集合协调性的快速改变。
Neuron. 2006 Oct 19;52(2):359-69. doi: 10.1016/j.neuron.2006.07.030.
4
The relationship between local field potential and neuronal discharge in the subthalamic nucleus of patients with Parkinson's disease.帕金森病患者丘脑底核局部场电位与神经元放电之间的关系。
Exp Neurol. 2005 Jul;194(1):212-20. doi: 10.1016/j.expneurol.2005.02.010.
5
Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials.帕金森病灵长类动物皮质/基底神经节网络中的尖峰同步反映了局部场电位的全局动态。
J Neurosci. 2004 Jun 30;24(26):6003-10. doi: 10.1523/JNEUROSCI.4848-03.2004.
6
The basal ganglia and motor control.基底神经节与运动控制。
Neural Plast. 2003;10(1-2):107-20. doi: 10.1155/NP.2003.107.
7
Network synchrony in the nucleus accumbens in vivo.伏隔核内的体内网络同步性。
J Neurosci. 2001 Jun 15;21(12):4498-504. doi: 10.1523/JNEUROSCI.21-12-04498.2001.
8
Signals and signs in the nervous system: the dynamic anatomy of electrical activity is probably information-rich.神经系统中的信号与体征：电活动的动态解剖结构可能蕴含丰富信息。
Proc Natl Acad Sci U S A. 1997 Jan 7;94(1):1-6. doi: 10.1073/pnas.94.1.1.
9
Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic.多巴胺缺乏的小鼠严重活动减退、无饮欲和无食欲。
Cell. 1995 Dec 29;83(7):1197-209. doi: 10.1016/0092-8674(95)90145-0.
10
Parkinson's disease and the adaptive capacity of the nigrostriatal dopamine system: possible neurochemical mechanisms.帕金森病与黑质纹状体多巴胺系统的适应能力：可能的神经化学机制
Adv Neurol. 1993;60:140-7.

Many Roads to Motor Deficits: Loss of Dopamine Signaling in Direct or Indirect Basal Ganglia Pathway Leads to Akinesia through Distinct Physiological Mechanisms.

作者信息

Calhoon Gwendolyn G, O'Donnell Patricio

机构信息

Department of Anatomy and Neurobiology, University of Maryland School of Medicine Baltimore, MD, USA.

出版信息

Front Neurosci. 2010 Dec 8;4:168. doi: 10.3389/fnins.2010.00168. eCollection 2010.

DOI:10.3389/fnins.2010.00168
PMID:21151744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3000179/
Abstract
摘要