Many Roads to Motor Deficits: Loss of Dopamine Signaling in Direct or Indirect Basal Ganglia Pathway Leads to Akinesia through Distinct Physiological Mechanisms.
作者信息
Calhoon Gwendolyn G, O'Donnell Patricio
机构信息
Department of Anatomy and Neurobiology, University of Maryland School of Medicine Baltimore, MD, USA.
出版信息
Front Neurosci. 2010 Dec 8;4:168. doi: 10.3389/fnins.2010.00168. eCollection 2010.
Abstract
摘要
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Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's disease.在帕金森病模型中，纹状体中等棘状神经元的反复侧支连接受到破坏。
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Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction.急性多巴胺依赖性运动功能障碍期间皮质纹状体集合协调性的快速改变。
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Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials.帕金森病灵长类动物皮质/基底神经节网络中的尖峰同步反映了局部场电位的全局动态。
J Neurosci. 2004 Jun 30;24(26):6003-10. doi: 10.1523/JNEUROSCI.4848-03.2004.
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The basal ganglia and motor control.基底神经节与运动控制。
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Network synchrony in the nucleus accumbens in vivo.伏隔核内的体内网络同步性。
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Signals and signs in the nervous system: the dynamic anatomy of electrical activity is probably information-rich.神经系统中的信号与体征：电活动的动态解剖结构可能蕴含丰富信息。
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