帕金森病：它是一种中毒综合征吗？
Parkinson's disease: is it a toxic syndrome?
作者信息
Gad Elhak Seham A, Ghanem Abdel Aziz A, Abdelghaffar Hassan, El Dakroury Sahar, Salama Mohamed M
机构信息
Toxicology Department, Faculty of Medicine, Mansoura University, Mansoura 35111, Egypt.
出版信息
Neurol Res Int. 2010;2010:103094. doi: 10.1155/2010/103094. Epub 2010 Sep 5.
Abstract
Parkinson's disease (PD) is one of the neurodegenerative diseases which we can by certainty identify its pathology, however, this confidence disappeares when talking about the cause. A long history of trials, suggestions, and theories tried linking PD to a specific causation. In this paper, a new suggestion is trying to find its way, could it be toxicology? Can we-in the future-look to PD as an occupational disease, in fact, many clues point to the possible toxic responsibility-either total or partial-in causing this disease. Searching for possible toxic causes for PD would help in designing perfect toxic models in animals.
摘要
帕金森病（PD）是一种我们能够确切识别其病理的神经退行性疾病，然而，当谈及病因时，这种确定性就消失了。长期以来，一系列的试验、推测和理论都试图将帕金森病与特定病因联系起来。在本文中，一种新的推测正在探索出路，它会是毒理学吗？未来我们能否将帕金森病视为一种职业病？事实上，许多线索都指向了在引发这种疾病中可能存在的全部或部分毒性责任。寻找帕金森病可能的毒性病因将有助于设计完善的动物毒性模型。
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