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静脉注射海洛因所致颈椎骨髓炎:14例患者的影像学表现

Cervical osteomyelitis due to i.v. heroin use: radiologic findings in 14 patients.

作者信息

Endress C, Guyot D R, Fata J, Salciccioli G

机构信息

Department of Radiology, Detroit Receiving Hospital, Wayne State University, MI 48201.

出版信息

AJR Am J Roentgenol. 1990 Aug;155(2):333-5. doi: 10.2214/ajr.155.2.2115262.

Abstract

We reviewed the radiographs of 14 patients who had cervical osteomyelitis and were IV heroin users. Eleven were men and three were women. Their age range was 33-48 years (mean, 39 years). Eleven regularly used the jugular vein access, and three alternated between the jugular and femoral veins. Initial radiographs of the cervical spine in 13 patients showed destruction of two or more vertebral bodies and the adjacent intervertebral disk, as well as a prevertebral soft-tissue mass. In one patient, findings on initial radiographs were normal, but marked destruction at two contiguous intervertebral levels and a large prevertebral abscess were identified 2 weeks later. All the patients had positive results on cultures of joint aspirates or bone biopsy materials (10 patients) or blood (four patients). Ten grew Staphylococcus aureus; two, Staphylococcus epidermidis; one, Streptococcus viridans; and one, Pseudomonas aeruginosa. CT in nine patients showed inflammatory reaction adjacent to the carotid sheath resulting from the repeated jugular injections and delineated the extent of prevertebral abscess and bone destruction. Scintigrams were of minimal value in establishing the diagnosis. Advanced vertebral body destruction, disk space infection, prevertebral abscess, and anterior cervical inflammatory reaction appear to be typical findings on radiographs in heroin abusers with cervical osteomyelitis.

摘要

我们回顾了14例患有颈椎骨髓炎且为静脉注射海洛因使用者的X线片。其中11例为男性,3例为女性。年龄范围为33 - 48岁(平均39岁)。11例经常使用颈静脉通路,3例在颈静脉和股静脉之间交替使用。13例患者颈椎的初始X线片显示两个或更多椎体及相邻椎间盘破坏,以及椎前软组织肿块。1例患者初始X线片结果正常,但2周后发现两个连续椎间水平有明显破坏及一个大的椎前脓肿。所有患者关节穿刺液或骨活检材料(10例)或血液(4例)培养结果均为阳性。10例培养出金黄色葡萄球菌;2例培养出表皮葡萄球菌;1例培养出草绿色链球菌;1例培养出铜绿假单胞菌。9例患者的CT显示因反复颈静脉注射导致颈动脉鞘周围的炎症反应,并勾勒出椎前脓肿和骨质破坏的范围。骨闪烁造影在确立诊断方面价值极小。椎体严重破坏、椎间盘间隙感染、椎前脓肿和颈椎前炎症反应似乎是海洛因成瘾者颈椎骨髓炎X线片的典型表现。

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