Department of cardiothoracic and Vascular Surgery, University Hopsital Mainz, Germany.
Cardiol J. 2010;17(6):574-9.
There is ongoing discussion as to whether it is beneficial to avoid pulmonary sinus augmentation in the arterial switch operation. We report a single-surgeon series of mid-term results for direct pulmonary artery anastomosis during switch operation for transposition of the great arteries (TGA).
This retrospective study includes 17 patients with TGA, combined with an atrial septal defect, patent foramen ovale or ventricular septal defect. Patient data was analyzed from hospital charts, including operative reports, post-operative course, and regular follow-up investigations. The protocol included cardiological examination by a single pediatric cardiologist. Echocardiographic examinations were performed immediately after arrival on the intensive unit, before discharge, and then after three, six, and 12 months, followed by yearly intervals. Pulmonary artery stenosis (PAS) was categorized into three groups according to the Doppler-measured pulmonary gradient: grade I (trivial stenosis) = increased pulmonary flow with a gradient below 25 mm Hg; grade II (moderate stenosis) = a gradient ranging from 25 to 49 mm Hg; and grade III (severe stenosis) = a gradient above 50 mm Hg. Follow-up data was available for all patients. The length of follow-up ranged from 1.2 to 9.7 years, median: 7.5 years (mean 6.1 years ± 14 months).
During follow-up, 12 patients (70.6%) had no (or only trivial) PAS, five patients (29.4%) had moderate stenosis without progress, and no patient had severe PAS. Cardiac catheterization after arterial switch operation was performed in 11 patients (64.7%) and showed a good correlation with echocardiographic findings. During follow-up there was no reintervention for PAS.
Direct reconstruction of the neo-pulmonary artery is a good option in TGA with antero-posterior position of the great vessels, with very satisfactory mid-term results.
目前对于在大动脉调转术(arterial switch operation,ASO)中是否有必要避免肺动静脉窦增宽存在争议。我们报告了一组由同一位外科医生完成的大动脉调转术同期行肺动脉直接吻合术治疗完全性大动脉转位(transposition of the great arteries,TGA)的中期结果。
本回顾性研究纳入了 17 例 TGA 合并房间隔缺损、卵圆孔未闭或室间隔缺损患者。从病历中分析患者数据,包括手术报告、术后病程以及定期随访检查。方案包括由一名儿科心脏病专家进行心脏检查。患者入住重症监护病房后即刻、出院前以及 3、6、12 个月后进行超声心动图检查,之后每年复查。根据多普勒测量的肺动脉梯度将肺动脉狭窄(pulmonary artery stenosis,PAS)分为 3 组:Ⅰ级(轻度狭窄)=肺动脉血流增加且梯度<25mmHg;Ⅱ级(中度狭窄)=梯度 25-49mmHg;Ⅲ级(重度狭窄)=梯度>50mmHg。所有患者均获得随访数据。随访时间为 1.2-9.7 年,中位数 7.5 年(平均 6.1 年±14 个月)。
随访期间,12 例患者(70.6%)无狭窄(或仅轻度狭窄),5 例患者(29.4%)为中度狭窄且无进展,无患者为重度狭窄。11 例患者(64.7%)接受了大动脉调转术后的心脏导管检查,结果与超声心动图检查具有良好的相关性。随访期间无 PAS 再介入治疗。
对于大血管前后位的 TGA,行肺动脉直接重建是一种较好的选择,具有非常满意的中期结果。