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Piezosurgery 医疗器械在大鼠耳蜗钻孔中的作用。

Effects of cochlear drilling with Piezosurgery Medical device in rats.

机构信息

Department of Otolaryngology/Head and Neck Surgery, Dallas, Texas USA.

出版信息

Laryngoscope. 2011 Jan;121(1):182-6. doi: 10.1002/lary.21166.

DOI:10.1002/lary.21166
PMID:21154673
Abstract

OBJECTIVES/HYPOTHESIS: Drilling on the otic capsule for cochleostomy should be less traumatic to the cochlea with the Piezosurgery Medical device (PZ) than with a standard diamond drill (DD). "Soft" cochleostomy is used for preservation of residual hearing in cochlear implant patients. PZ drilling can be used for accurate cochleostomy placement with minimal soft-tissue damage and may be superior for atraumatic drilling on the cochlea, as compared with a DD. This study compared inner ear effects after drilling the rat otic capsule with the PZ versus the DD.

STUDY DESIGN

Prospective animal study using rats.

METHODS

Otic capsule drilling was performed on the left ear with the DD (n = 5) or the PZ (n = 5), while otic capsule temperature was monitored. Contralateral ears served as controls. The animals were sacrificed after 1 week. Organ of Corti damage was morphologically evaluated and compared between groups.

RESULTS

Basal turn hair cell loss was observed in all ears in the PZ group, regardless of drilling depth. However, no cochlear damage was found in any ears in the DD group.

CONCLUSIONS

Otic capsule drilling with the PZ results in greater trauma to the rat inner ear than drilling using conventional methods.

摘要

目的/假设:与标准金刚石钻头(DD)相比,Piezosurgery Medical 设备(PZ)在耳科囊上进行耳蜗造瘘术对耳蜗的创伤应该更小。“软性”耳蜗造瘘术用于保留耳蜗植入患者的残余听力。与 DD 相比,PZ 钻孔可用于准确放置耳蜗造瘘术,对软组织结构的损伤最小,并且可能更适合于对耳蜗进行无创伤性钻孔。本研究比较了使用 PZ 与 DD 对大鼠耳科囊进行钻孔后的内耳影响。

研究设计

使用大鼠的前瞻性动物研究。

方法

使用 DD(n = 5)或 PZ(n = 5)对左侧耳科囊进行钻孔,同时监测耳科囊温度。对侧耳朵作为对照。动物在 1 周后被处死。对各组之间的形态学评估和比较毛细胞损伤。

结果

无论钻孔深度如何,PZ 组所有耳朵的基底回毛细胞均有丢失,但 DD 组任何耳朵均未发现耳蜗损伤。

结论

与传统方法相比,使用 PZ 进行耳科囊钻孔会对大鼠内耳造成更大的创伤。

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Effects of cochlear drilling with Piezosurgery Medical device in rats.Piezosurgery 医疗器械在大鼠耳蜗钻孔中的作用。
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