Department of Anesthesia, Intensive Care and Pain Medicine, Zaans Medical Centre, Zaandam, The Netherlands.
Anesth Analg. 2011 Mar;112(3):719-24. doi: 10.1213/ANE.0b013e318206bc30. Epub 2010 Dec 14.
Hemodynamic variables can theoretically be influenced by a combined psoas compartment-sciatic nerve block (CPCSNB) owing to a relatively high systemic absorption of local anesthetics and extended vasodilatation in the anesthetized limb (hemisympatectomy). In this study we assessed and documented hemodynamic changes during CPCSNB for elective orthopedic surgery.
Twenty consecutive patients scheduled for a total hip arthroplasty revision surgery were subjected to a CPCSNB with 150 mg bupivacaine (with epinephrine 1:200.000) 90 minutes before surgery (2 separate single-injection blocks: 30 mg bupivacaine for the sciatic nerve block and 120 mg bupivacaine for the psoas compartment block). Cardiac index, invasive arterial blood pressure, and heart rate were measured at baseline and 60 minutes after puncture using a minimally invasive cardiac output monitoring device (FloTrac/Vigileo™ system (Edwards Lifesciences, Irvine, CA)).
Cardiac index did not change after a CPCSNB (preblock cardiac index 2.98 ± 0.54 l · min(-1) · m(-2) versus postblock cardiac index 2.99 ± 0.60 l · min(-1) · m(-2)). There was a significant reduction in mean arterial blood pressure (108 ± 16 mm|Hg vs. 99 ± 16 mm|Hg (P < 0.001)) and diastolic blood pressure (75 ± 9 mm|Hg vs. 68 ± 10 mm|Hg (P = 0.001)). Heart rate increased significantly (68 ± 9 beats · min(-1) vs. 73 ± 10 beats · min(-1) (P = 0.001)).
CPCSNB did not affect cardiac index. Changes in arterial blood pressure and heart rate, although statistically significant, remained within an acceptable clinical range (<10% variation). CPCSNB does not appear to induce clinically significant hemodynamic changes in this group of patients.
由于局部麻醉剂的全身吸收相对较高以及麻醉肢体的血管扩张(半交感神经切除术),理论上,血流动力学变量可能会受到腰大肌腔隙-坐骨神经阻滞(CPCSNB)的影响。在这项研究中,我们评估并记录了用于择期骨科手术的 CPCSNB 期间的血流动力学变化。
连续 20 例接受全髋关节翻修手术的患者在手术前 90 分钟接受了 150mg 布比卡因(含肾上腺素 1:200000)的 CPCSNB(2 个单独的单次注射阻滞:30mg 布比卡因用于坐骨神经阻滞,120mg 布比卡因用于腰大肌腔隙阻滞)。使用微创心输出量监测设备(FloTrac/Vigileo™系统(爱德华生命科学公司,加利福尼亚州欧文市))在基线和穿刺后 60 分钟测量心指数、有创动脉血压和心率。
CPCSNB 后心指数没有变化(前阻滞心指数 2.98±0.54l·min-1·m-2 与后阻滞心指数 2.99±0.60l·min-1·m-2)。平均动脉压(108±16mmHg 与 99±16mmHg(P<0.001))和舒张压(75±9mmHg 与 68±10mmHg(P=0.001))显著降低。心率显著增加(68±9 次·min-1 与 73±10 次·min-1(P=0.001))。
CPCSNB 不影响心指数。尽管动脉血压和心率的变化具有统计学意义,但仍在可接受的临床范围内(<10%的变化)。在这群患者中,CPCSNB 似乎不会引起明显的血流动力学变化。