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新生儿脊髓脊膜膨出修补术后立即应用低强度激光治疗的新型疗法:一项初步研究。

Novel treatment immediately after myelomeningocele repair applying low-level laser therapy in newborns: a pilot study.

作者信息

Pinto Fernando C, Chavantes M Cristina, Pinto Nathali C, Alho Eduardo J L, Yoshimura Elisabeth M, Matushita Hamilton, Krebs Vera L J, Teixeira Manoel J

机构信息

Division of Functional Neurosurgery of the Institute of Psychiatry, University of São Paulo, São Paulo, Brazil.

出版信息

Pediatr Neurosurg. 2010;46(4):249-54. doi: 10.1159/000319363. Epub 2010 Dec 15.

Abstract

BACKGROUND/AIMS: The use of low-level laser therapy (LLLT) in neurosurgery is still hardly disseminated and there are situations in which the effects of this therapeutic tool would be extremely relevant in this medical field. The aim of the present study is to analyze the effect of LLLT on tissue repair after the corrective surgical incision in neonates with myelomeningocele, in an attempt to diminish the incidence of postoperative dehiscences following surgical repair performed immediately after birth.

MATERIALS AND METHODS

Prospective pilot study with 13 patients submitted to surgery at birth who received adjuvant treatment with LLLT (group A). A diode laser CW, λ = 685 nm, p = 21 mW, was applied punctually along the surgical incision, with 0.19 J delivered per point, accounting for a total of 4-10 J delivered energy per patient, according to the surgical wound area and then compared with the results obtained in 23 patients who underwent surgery without laser therapy (group B).

RESULTS

This pilot study disclosed a significant decline in dehiscences of the surgical wounds in neonates who were submitted to LLLT (7.69 vs. 17.39%).

CONCLUSION

This new adjuvant therapeutic modality with LLLT aided the healing of surgical wounds, preventing morbidities, as well as shortening the period of hospital stay, which implies a reduction of costs for patients and for the institution.

摘要

背景/目的:低强度激光疗法(LLLT)在神经外科手术中的应用仍未广泛普及,而在该医学领域的某些情况下,这种治疗工具的效果可能极为显著。本研究的目的是分析LLLT对患有脊髓脊膜膨出的新生儿进行矫正手术切口后组织修复的影响,以试图降低出生后立即进行手术修复后的术后切口裂开发生率。

材料与方法

对13例出生时接受手术并接受LLLT辅助治疗的患者进行前瞻性试点研究(A组)。使用连续波二极管激光,波长λ = 685 nm,功率p = 21 mW,沿手术切口逐点照射,每点输送能量0.19 J,根据手术伤口面积,每位患者输送的总能量为4 - 10 J,然后与23例未接受激光治疗的手术患者(B组)的结果进行比较。

结果

这项试点研究表明,接受LLLT治疗的新生儿手术伤口裂开情况显著减少(7.69%对17.39%)。

结论

这种新的LLLT辅助治疗方式有助于手术伤口愈合,预防并发症,还缩短了住院时间,这意味着患者和医疗机构的成本降低。

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