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80 岁以上老人的腰椎融合术:微创的承诺。

Lumbar fusion in octogenarians: the promise of minimally invasive surgery.

机构信息

Spine Midwest Inc., Jefferson City, MO, USA.

出版信息

Spine (Phila Pa 1976). 2010 Dec 15;35(26 Suppl):S355-60. doi: 10.1097/BRS.0b013e3182023796.

Abstract

STUDY DESIGN

Retrospective chart review of prospectively collected data from 2 nonrandomized, nonconcurrent cohorts.

OBJECTIVE

Early results of 2 lumbar interbody fusion procedures-open posterior lumbar interbody fusion (PLIF) and minimally invasive (extreme lateral interbody fusion [XLIF])-were compared in octogenarians to demonstrate the safety of each in the extreme elderly populations.

SUMMARY OF BACKGROUND DATA

Although spinal pathologies are common in the elderly patients, additional health conditions often preclude operative treatment because anesthesia, blood loss, and recovery are too demanding. Minimally invasive approaches reduce procedure-related morbidity and recovery time.

METHODS

In our single-site prospective series of XLIF patients, 40 were identified as those aged ≥80 years with a minimum of 3-month follow-up. A complete, retrospective review of surgical patients treated in the same practice with traditional open posterior (PLIF) approach found 20 patients aged ≥80 years. Comparisons were made between groups to identify differences in morbidity and mortality rates.

RESULTS

No clinically significant differences in demographics, diagnoses, or comorbidities were found between groups. Complication rate, blood loss/transfusion rate, and hospital stay were significantly lower in the minimally invasive surgery (MIS) group (P < 0.0001). MIS patients left the hospital an average of 4 days earlier than the open PLIF patients, most discharged home (92.5% XLIF vs. 0% PLIF) rather than to skilled nursing facilities. Six deaths occurred in the PLIF follow-up, 3 within 3 months postoperatively; there was 1 death at 6 months postoperatively XLIF.

CONCLUSION

Surgical treatment need not be withheld on the basis of age; elderly patients can successfully be treated using MIS techniques, and are-in our experience-among the most satisfied with their outcomes, enjoying significant improvements in pain, mobility, and quality of life.

摘要

研究设计

回顾性分析前瞻性收集的 2 组非随机、非同期数据。

目的

比较两种腰椎体间融合术-开放后路腰椎体间融合术(PLIF)和微创(极外侧腰椎体间融合术[XLIF])-在 80 岁以上患者中的早期结果,以证明每种方法在极高龄人群中的安全性。

背景资料总结

虽然脊柱病变在老年患者中很常见,但由于麻醉、失血和恢复过程要求过高,其他健康状况往往会排除手术治疗。微创方法可降低与手术相关的发病率和恢复时间。

方法

在我们的单站点前瞻性 XLIF 患者系列中,确定了 40 名年龄≥80 岁且至少随访 3 个月的患者。对在同一实践中接受传统开放后路(PLIF)方法治疗的手术患者进行了完整的回顾性审查,发现了 20 名年龄≥80 岁的患者。对两组患者进行了比较,以确定发病率和死亡率的差异。

结果

两组在人口统计学、诊断或合并症方面无明显差异。微创组(MIS)的并发症发生率、失血量/输血率和住院时间明显较低(P<0.0001)。MIS 患者平均比开放 PLIF 患者提前 4 天出院,大多数出院回家(92.5%XLIF 比 0%PLIF),而非到疗养院。PLIF 随访中有 6 例死亡,3 例发生在术后 3 个月内;XLIF 术后 6 个月有 1 例死亡。

结论

手术治疗不应因年龄而被拒绝;老年患者可以成功地接受微创技术治疗,并且-根据我们的经验-他们是对治疗结果最满意的人群之一,在疼痛、活动能力和生活质量方面都有显著改善。

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