Department of Neurosurgery, Nagoya University Graduate School of Medicine.
Department of Orthopedic Surgery, Spine Center, Konan Kosei Hospital.
Neurol Med Chir (Tokyo). 2023 Dec 15;63(12):548-554. doi: 10.2176/jns-nmc.2023-0064. Epub 2023 Oct 18.
There is a lack of agreement on whether minimally invasive lateral lumbar intervertebral fusion (LLIF) is a suitable treatment option for vertebral fragility fractures (VFFs). Hence, we sought to evaluate the efficacy and safety of LLIF in the management of VFF with neurological deficits in the lumbar spine. Between April 2015 and March 2020, we conducted a retrospective observational study of patients with VFF treated with three-level or less LLIF. The participants had previously received conservative treatment but had not been able to control their neurological symptoms. To assess the outcomes of the LLIF procedures, the patients were followed up for a minimum of 1 year. Clinical and radiological results, which include the timing and location of the bony fusion, were analyzed. The study involved 19 patients with 23 vertebral fracture levels. The residual height of the fractured vertebra was found to be 57.0 ± 12.3% of the height of the adjacent level. The mean Japanese Orthopedic Association score significantly improved postoperatively. Postoperative radiological parameters were significantly maintained at 1 year, and lumbar lordosis was maintained at the last follow-up (45.0 ± 26.7). In total 31 LLIF levels, bone fusion was observed in four levels at 6 months postoperatively, in 16 levels at 1 year, and in 23 levels at the last follow-up. The facet joint had the highest bony fusion location. LLIF within three levels can be safely performed in certain VFF cases with sufficient residual vertebral height.
对于微创侧方腰椎椎间融合术(LLIF)是否适合治疗腰椎脆弱性骨折(VFF),目前尚无共识。因此,我们旨在评估 LLIF 在治疗伴有神经功能缺损的腰椎 VFF 中的疗效和安全性。2015 年 4 月至 2020 年 3 月,我们对接受三平面或以下 LLIF 治疗的 VFF 患者进行了回顾性观察性研究。这些患者先前接受过保守治疗,但无法控制其神经症状。为了评估 LLIF 手术的结果,对患者进行了至少 1 年的随访。分析了临床和影像学结果,包括骨融合的时间和部位。该研究共纳入 19 例 23 个椎体骨折节段的患者。骨折椎体的残余高度为相邻节段高度的 57.0±12.3%。日本矫形协会评分(JOA)术后显著改善。术后影像学参数在 1 年时得到显著维持,腰椎前凸在末次随访时(45.0±26.7)得以维持。在总共 31 个 LLIF 节段中,术后 6 个月有 4 个节段观察到骨融合,术后 1 年有 16 个节段,末次随访时有 23 个节段观察到骨融合。关节突关节是骨融合的最高部位。在有足够残余椎体高度的特定 VFF 病例中,可安全地进行三平面内的 LLIF。