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产褥期急性肾衰竭与消耗性凝血病

[Acute renal failure and consumption coagulopathy in the puerperium].

作者信息

Larcan A, Lambert H, Laprevote-Heully M C, Alexandre P, Gerbaux A

出版信息

Sem Hop. 1978 Jun;54(17-20):595-601.

PMID:211607
Abstract

Disseminated intravascular coagulation accompanied 18% of cases of acute renal failure during puerperal disorders. We studied in particular 31 cases of disseminated intravascular coagulation with renal failure due to obstetric disorders : 12 post-abortion infections, 3 retentions of a dead foetus, 5 infections, 6 cases of toxemia, 2 retroplacental hemorrhages, two hemorrhages during the third stage, one uremohemolytic syndrome. For diagnosis one relies on the clinical data (bleeding, purpura, shock, hemolysis, visceral involvement) and laboratory data, (coagulation should be supervised throughout the course). The renal lesions are either cortical necrosis, or interstitial nephritis. The analogies with experimental phenomena suggest a human equivalent of the Schwartzmann-Sanarelli syndrome.

摘要

在产褥期疾病中,18%的急性肾衰竭病例伴有弥散性血管内凝血。我们特别研究了31例因产科疾病导致肾衰竭的弥散性血管内凝血病例:12例流产后感染、3例死胎滞留、5例感染、6例毒血症、2例胎盘后出血、第三产程中的2例出血、1例尿毒症性溶血综合征。诊断依赖于临床资料(出血、紫癜、休克、溶血、内脏受累)和实验室资料(整个病程中都应监测凝血情况)。肾脏病变要么是皮质坏死,要么是间质性肾炎。与实验现象的相似性提示存在人类等效的施瓦茨曼-萨纳雷利综合征。

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