Burdina L M, Smetnik V P, Volobuev A I
Akush Ginekol (Mosk). 1990 Apr(4):47-50.
This study included 62 women with hypergonadotropic amenorrhea. Clinical, hormonal, genetic, laparoscopic and histologic studies revealed three types of the disease: resistant ovary syndrome, dystrophic ovary syndrome, and "pure" gonadal dysgenesis. Mammary function and architectonics were correlated with gynecologic conditions. Fibrocystic breast disease was identified in 64.9% of patients with resistant ovary syndrome, and fatty glandular degeneration was seen in dystrophic ovary syndrome; pure gonadal dysgenesis was associated with breast hypoplasia, poor structural differentiation and prevalence of adipose tissue in the mammary glands.
本研究纳入了62例高促性腺激素性闭经的女性。临床、激素、遗传学、腹腔镜及组织学研究揭示了该疾病的三种类型：卵巢抵抗综合征、卵巢营养不良综合征和“单纯”性腺发育不全。乳腺功能和结构与妇科情况相关。在64.9%的卵巢抵抗综合征患者中发现了纤维囊性乳腺病，在卵巢营养不良综合征中可见脂肪性腺变性；单纯性腺发育不全与乳腺发育不全、结构分化不良及乳腺中脂肪组织的普遍存在有关。
