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计算机断层扫描在结直肠癌管理中的应用。

Use of computed tomography in the management of colorectal cancer.

作者信息

Tan Cher Heng, Iyer Revathy

机构信息

Cher Heng Tan, Department of Diagnostic Radiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.

出版信息

World J Radiol. 2010 May 28;2(5):151-8. doi: 10.4329/wjr.v2.i5.151.

DOI:10.4329/wjr.v2.i5.151
PMID:21161029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2999018/
Abstract

Computed tomography (CT) plays an important role in the management of colorectal cancer (CRC). The use of CT (colonography) as a screening tool for CRC has been validated and is expected to rise over time. The results of prior studies suggest that CT is suboptimal for assessment of local T stage and moderate for N stage disease. Recent advances in CT technology are expected to lead to some improvement in staging accuracy. At present, the main role of CT in pre-treatment imaging assessment lies in its use for the detection of distant metastases, especially in the liver. In a select group of patients, routine post-treatment surveillance with CT confers survival benefits. The role of CT for post-treatment assessment has been radically altered and improved with the advent of fusion positron emission tomography/CT. Perfusion CT shows promise as another functional imaging modality but further experience with this technique is necessary before it can be applied to routine clinical practice.

摘要

计算机断层扫描(CT)在结直肠癌(CRC)的管理中发挥着重要作用。CT(结肠成像)作为CRC筛查工具的应用已得到验证,并且预计随着时间推移其使用会增加。先前研究结果表明,CT在评估局部T分期方面欠佳,在评估N分期疾病方面表现中等。CT技术的最新进展有望在分期准确性方面带来一些改善。目前,CT在治疗前影像评估中的主要作用在于用于检测远处转移,尤其是在肝脏。在一组特定患者中,CT常规治疗后监测可带来生存获益。随着融合正电子发射断层扫描/CT的出现,CT在治疗后评估中的作用已发生根本性改变并得到改善。灌注CT作为另一种功能成像方式显示出前景,但在将该技术应用于常规临床实践之前,还需要更多经验。

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World J Gastroenterol. 2009 Jul 14;15(26):3228-31. doi: 10.3748/wjg.15.3228.
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Feasibility of integrated CT-liver perfusion in routine FDG-PET/CT.常规FDG-PET/CT中CT肝脏灌注成像的可行性。
Abdom Imaging. 2010 Oct;35(5):528-36. doi: 10.1007/s00261-009-9559-y. Epub 2009 Jul 11.
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Multislice CT as a primary screening tool for the prediction of an involved mesorectal fascia and distant metastases in primary rectal cancer: a multicenter study.多层螺旋CT作为预测原发性直肠癌中直肠系膜筋膜受累及远处转移的主要筛查工具:一项多中心研究
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Tailoring therapy in colorectal cancer by PET-CT.利用正电子发射断层显像-计算机断层扫描(PET-CT)对结直肠癌进行个体化治疗
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5
Diagnostic accuracy of serial CT/magnetic resonance imaging review vs. positron emission tomography/CT in colorectal cancer patients with suspected and known recurrence.在疑似和已知复发的结直肠癌患者中,连续CT/磁共振成像复查与正电子发射断层扫描/CT的诊断准确性比较
Dis Colon Rectum. 2009 Feb;52(2):253-9. doi: 10.1007/DCR.0b013e31819d11e6.
6
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Eur Radiol. 2009 Jun;19(6):1366-78. doi: 10.1007/s00330-008-1289-y. Epub 2009 Feb 4.
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