应用于氮化硅衬底上的银纳米颗粒复合物稳定性的模拟生物介质效应
Effect of model biological media of stability of complex of silver nanoparticles applied onto silicon nitride substrate.
作者信息
Afanasiev S A, Tsapko L P, Kurzina I A, Chuhlomina L N, Babokin V E
机构信息
Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences.
出版信息
Bull Exp Biol Med. 2010 Dec;150(1):160-4. doi: 10.1007/s10517-010-1093-y.
We studied stability of complexes of silver nanoparticles and silicon nitride before and after their interaction with liquid media and after passing through bacterial filters. According to scanning electron microscopy data, contact with fluids and passage through bacterial filters reduced the content of silver nanoparticles in complexes compared to that in initial complexes. It was shown that these differences depended on both initial characteristics of the examined samples and the used liquid media. The complex Ag/Si3N4 obtained after 5 silver reduction cycles and containing 15% α- and 85% β-modifications of silicon nitride (sample No. 2) was characterized by maximum stability. Culture medium produced more aggressive effect on stability of the studied complexes. We concluded that the effect of culture media on stability of silver nanoparticles-silicon nitride complexes depends on phase composition of the substrate and method of application of silver nanoparticles.
我们研究了银纳米颗粒与氮化硅的复合物在与液体介质相互作用之前和之后以及通过细菌过滤器后的稳定性。根据扫描电子显微镜数据，与初始复合物相比，与流体接触和通过细菌过滤器会降低复合物中银纳米颗粒的含量。结果表明，这些差异既取决于所检测样品的初始特性，也取决于所使用的液体介质。经过5次银还原循环后获得的含有15%α-和85%β-氮化硅变体的Ag/Si3N4复合物（样品编号2）具有最大稳定性。培养基对所研究复合物的稳定性产生了更具侵蚀性的影响。我们得出结论，培养基对银纳米颗粒-氮化硅复合物稳定性的影响取决于底物的相组成和银纳米颗粒的应用方法。
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