Bouchard P, Lubrano M F, Banssillon V G
Sem Hop. 1978 Jun;54(17-20):675-7.
The psycho-motor sedative action of tiapride, which has been demonstrated in internal medicine, was studied in anesthesiology. A group of 253 patients hospitalized for urological (203 cases) or gynaecological (50 cases) operations were given standard premedication together with 100 to 300 mg of tiapride. Preoperative sedation and reduction of anxiety was excellent in 138 cases, moderate in 97 cases, and nil in 18 cases, under the influence of tiapride. Tiapride was perfectly well tolerated even in patients with debility, obesity, alcoholism and cardiac or respiratory insufficiency.
已在内科证实具有精神运动性镇静作用的硫必利,在麻醉学领域进行了研究。一组因泌尿外科手术(203例)或妇科手术(50例)住院的253例患者,在接受标准术前用药的同时,给予100至300毫克硫必利。在硫必利的作用下,138例患者术前镇静及焦虑减轻效果极佳,97例效果中等,18例无效果。即使是身体虚弱、肥胖、酗酒以及有心脏或呼吸功能不全的患者,对硫必利的耐受性也非常好。