Huang Zhen-guo, Zhang Xue-zhe, Wang Wu, Hong Wen, Ren An
Department of Radiology, China-Japan Friendship Hospital, Beijing 100029, China.
Zhonghua Yi Xue Za Zhi. 2010 Oct 26;90(39):2745-9.
To investigate the relationship between imaging and pathological findings of avascular necrotic of the femoral head (ANFH).
A comparison among of conventional radiography, computerized tomography (CT), magnetic resonance imaging (MRI), gross section and pathological examinations was performed in 20 femoral heads in 15 patients undergoing total hip replacement for established ANFH.
ANFH involved the anterosuperior aspect of femoral head in all hips. Necrotic femoral heads consisted of cartilage, necrotic area, reactive repaired area and extralesional area. The reactive repaired area surrounded necrotic area. Imaging findings: 1) on conventional radiography and CT, as compared with the extralesional area, the necrotic area appeared to be of an equal density (11), a lower density (7) and a higher density (2) On MRI, the necrotic areas revealed adipose intensity (3), blood like intensity (1), aquatic intensity (2), fibrous intensity (9) and non-homogeneous intensity (5); 2) the reactive repaired area separated the necrotic and extralesional areas. Both on plain radiography and CT, the reactive repaired area showed a sclerotic band surrounding the necrotic area and a hypo-density inner line adjacent to sclerotic band was seen in 11 femoral heads on CT and 7 on conventional radiography. A band of low signal in the proliferative zone was seen on MRI in all hips and a rim of high signal intensity inside the low-signal margin (double-line sign) was seen in 3 hips on T2W images.
Conventional radiography, CT and MRI can display the grossly discernable necrotic, reactive repaired and extralesional areas accurately. Characteristic imaging findings are observed in the reactive repaired area.
探讨股骨头缺血性坏死(ANFH)的影像学表现与病理结果之间的关系。
对15例因确诊ANFH而行全髋关节置换术患者的20个股骨头进行了传统X线摄影、计算机断层扫描(CT)、磁共振成像(MRI)、大体标本及病理检查,并进行对比分析。
所有髋关节的ANFH均累及股骨头的前上方。坏死的股骨头由软骨、坏死区、反应性修复区和病灶外区域组成。反应性修复区围绕坏死区。影像学表现:1)在传统X线摄影和CT上,与病灶外区域相比,坏死区密度表现为等密度(11例)、低密度(7例)和高密度(2例)。在MRI上,坏死区表现为脂肪信号强度(3例)、血样信号强度(1例)、水样信号强度(2例)、纤维信号强度(9例)和不均匀信号强度(5例);2)反应性修复区将坏死区与病灶外区域分隔开来。在平片和CT上,反应性修复区均表现为围绕坏死区的硬化带,在CT上11个股骨头及传统X线摄影上7个股骨头可见硬化带相邻的低密度内线。在所有髋关节的MRI上,增生区均可见低信号带,在T2加权图像上3个股骨头可见低信号边缘内的高信号环(双线征)。
传统X线摄影、CT和MRI能够准确显示肉眼可辨的坏死区、反应性修复区和病灶外区域。在反应性修复区观察到了特征性的影像学表现。