Labansat Y, Pignol F, Casanova P
Sem Hop. 1978 Mar;54(5-8):362-6.
Thirthy-three alcoholics, aged between 31 and 82 years, were treated for 7 to 30 days with tiapride. The dosage was 600 mg/day (200 mg 3 times daily) by mouth or 100 to 800 mg/day I.M. Out of 27 cases of tremor treated, there were 25 favourable results, one average result and one nil result. Insomnia and character disorders, e.g. anguish, depression, nightmares, hallucinations, were improved during the first few days of treatment in 27 cases out of 30. Out of 12 cases of algo-paresthesia of the lower limb treated, the were 9 good or excellent results, 2 average results and 1 nil result. A favourable result was observed in 7 cases out of nine in vomiting, water brash (3 cases out of 4), and in 16 cases out of 20 in anorexia. No clinical or laboratory disturbance attributable to tiapride was noted in our patients whose general health was often very poor.
33名年龄在31岁至82岁之间的酗酒者接受了硫必利治疗,疗程为7至30天。口服剂量为600毫克/天(200毫克,每日3次),或肌肉注射剂量为100至800毫克/天。在接受治疗的27例震颤病例中,25例效果良好,1例效果一般,1例无效。30例中有27例在治疗的头几天失眠和性格障碍(如痛苦、抑郁、噩梦、幻觉)有所改善。在接受治疗的12例下肢疼痛性感觉异常病例中,9例效果良好或极佳,2例效果一般,1例无效。9例呕吐病例中有7例效果良好,4例反酸病例中有3例效果良好,20例厌食病例中有16例效果良好。在我们那些总体健康状况通常很差的患者中,未发现任何可归因于硫必利的临床或实验室干扰。