Department of Neurosurgery, University of Florida, Gainesville, Florida, USA.
J Clin Neurosci. 2011 Feb;18(2):287-90. doi: 10.1016/j.jocn.2010.05.011. Epub 2010 Dec 15.
Rasmussen's encephalitis is characterized by seizures, progressive neurological deterioration and chronic inflammation of the brain. It typically presents in childhood and requires anatomic or functional hemispherectomy for seizure control. Here, we report an adult woman who presented with new onset, medically refractory seizures that were not progressive. The patient underwent a right anterior temporal lobectomy. The pathologic samples were consistent with Rasmussen's encephalitis. The patient remained seizure free until her last follow-up at 2 years. This is an example of unique adult onset Rasmussen's encephalitis, suggesting that this encephalitis represents a wide spectrum of presentations rather than a specific disease.
拉森氏脑炎的特征是癫痫发作、进行性神经功能恶化和大脑慢性炎症。它通常在儿童时期发病,需要进行解剖或功能性大脑半球切除术以控制癫痫发作。在此,我们报告了一例成年女性新发病例,表现为药物难治性非进行性癫痫发作。患者接受了右侧前颞叶切除术。病理样本符合拉森氏脑炎。患者在最后一次随访 2 年时仍未发生癫痫。这是一例独特的成人起病的拉森氏脑炎,提示这种脑炎表现为广泛的表现谱,而不是一种特定的疾病。