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Noradrenaline turnover in the tissues of uraemic rats.

作者信息

Ksiazek A, Solski J

机构信息

Department of Nephrology, Medical School, Lublin, Poland.

出版信息

Int Urol Nephrol. 1990;22(1):89-93. doi: 10.1007/BF02550441.

DOI:10.1007/BF02550441
PMID:2116379
Abstract

In female Wistar rats with acute renal failure a decrease of noradrenaline concentration in the heart, spleen and kidney was ascertained. Noradrenaline concentration after alpha-methyl-p-tyrosine and 6-hydroxydopamine in the heart, spleen and kidney was significantly lower than in the control group. In the adrenals a decrease of catecholamine level after alpha-methyl-p-tyrosine and 6-hydroxydopamine has been noted in the controls. The changes in tissue noradrenaline concentration are evidence of a dysfunction in the adrenergic nervous system in uraemic rats.

摘要

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本文引用的文献

1
Effects of urea on physiologic systems. I. Studies on monoamine oxidase activity.尿素对生理系统的影响。I. 单胺氧化酶活性的研究。
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2
Precursors of adrenal epinephrine and norepinephrine in vivo.体内肾上腺素和去甲肾上腺素的前体物质。
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Brain serotonin and catecholamine turnover in uremic rats.尿毒症大鼠脑内血清素和儿茶酚胺的更新率
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4
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A method for the determination of serotonin and norepinephrine in discrete areas of rat brain.一种测定大鼠脑离散区域中血清素和去甲肾上腺素的方法。
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Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain.大鼠脑小区域中5-羟色胺和5-羟吲哚乙酸的快速测定方法。
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7
Autonomic insufficiency in uremia as a cause of hemodialysis-induced hypotension.尿毒症中的自主神经功能不全作为血液透析引起的低血压的一个原因。
N Engl J Med. 1974 Mar 21;290(12):650-3. doi: 10.1056/NEJM197403212901203.
8
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Klin Wochenschr. 1973 Nov 15;51(22):1115-23. doi: 10.1007/BF01468306.
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[Studies on uremic sympathicopathy in vitro and in vivo].[尿毒症交感神经病变的体内外研究]
Dtsch Med Wochenschr. 1973 Aug 31;98(35):1630-2.
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Phenylalanine metabolism in chronic renal failure.
Nephron. 1974;13(5):365-71. doi: 10.1159/000180412.