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噬血细胞综合征与立克次体病。

Haemophagocytic syndrome and rickettsial diseases.

机构信息

AILMI (Associazione Italiana per la Lotta contro le Malattie infettive) Universit� di Messina, Messina, Italy.

Dipartimento di Patologia Umana, Università di Messina, Messina, Italy.

出版信息

J Med Microbiol. 2011 Apr;60(Pt 4):537-542. doi: 10.1099/jmm.0.025833-0. Epub 2010 Dec 16.

DOI:10.1099/jmm.0.025833-0
PMID:21163825
Abstract

Haemophagocytic lymphohistiocytosis is a rare but potentially fatal disease resulting from dysregulated activation and proliferation of lymphocytes. We present a case of haemophagocytic syndrome occurring in a 5-year-old Italian boy as a complication of Mediterranean spotted fever. The characteristics of this case have been analysed and contextualized among those of another 15 cases of haemophagocytic syndrome associated with rickettsial diseases found through a systematic review of the international literature.

摘要

噬血细胞性淋巴组织细胞增生症是一种罕见但潜在致命的疾病，源于淋巴细胞的失调激活和增殖。我们报告了一例地中海斑疹热并发症导致的 5 岁意大利男孩噬血细胞综合征。通过对国际文献的系统回顾，分析并将该病例的特征与另外 15 例与立克次体病相关的噬血细胞综合征病例进行了比较。

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