Department of aInternal Medicine, Hedi Chaker Hospital, Sfax, Tunisia.
Eur J Gastroenterol Hepatol. 2011 Feb;23(2):189-92. doi: 10.1097/MEG.0b013e328342349e.
Abdominal pain observed in Henoch-Schönlein purpura (HSP) is usually attributed to edema and hemorrhage in the small bowel wall, secondary to a small-vessel vasculitis. Pancreatitis secondary to HSP is extremely rare. Here we report a 53-year-old man presented with acute pancreatitis that developed into characteristic rashes seen during HSP at the second day of the clinical onset, together with arthritis and glomerulonephritis. HSP is a rare and benign cause of acute pancreatitis. This complication can occur as an initial manifestation of HSP. Elevated serum amylase level can be considered as the early diagnostic tool for HSP pancreatitis. The patients with HSP who have abdominal pain as their chief complaint should be evaluated for pancreatitis, by routine serum amylase and abdominal computed tomography scan, to plan the specific treatment and avoid unnecessary surgery.
过敏性紫癜(HSP)中观察到的腹痛通常归因于小血管炎引起的小肠壁水肿和出血。继发于 HSP 的胰腺炎极为罕见。我们在此报告一例 53 岁男性,以急性胰腺炎起病,在发病第二天出现 HSP 的特征性皮疹,同时伴有关节炎和肾小球肾炎。HSP 是急性胰腺炎的罕见且良性病因。这种并发症可作为 HSP 的首发表现。血清淀粉酶水平升高可作为 HSP 胰腺炎的早期诊断工具。以腹痛为主要表现的 HSP 患者应通过常规血清淀粉酶和腹部计算机断层扫描评估胰腺炎,以制定具体的治疗方案并避免不必要的手术。