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在临床研究环境中通过电子生成的医嘱集来增强参与者的安全性:一项医学信息学计划。

Enhancing participant safety through electronically generated medication order sets in a clinical research environment: a medical informatics initiative.

机构信息

Hospital Pharmacy Services, Mayo Clinic, St. Marys Hospital, Rochester, Minnesota, USA.

出版信息

Clin Transl Sci. 2010 Dec;3(6):312-5. doi: 10.1111/j.1752-8062.2010.00240.x.

DOI:10.1111/j.1752-8062.2010.00240.x
PMID:21167008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3076285/
Abstract

While clinical medicine is often well supported by health system information technology infrastructure, clinical research may need to create strategies to use clinical-medicine informational technology tools. The authors describe a medication-safety initiative that was carried out in a National Institutes of Health Clinical and Translational Science Award (CTSA)-sponsored clinical research environment. A web based, medical informatics application was designed and implemented that allowed research groups to build protocol specific, electronic medication templates that were subsequently used to create participant-specific medication order sets for conductance of clinical research activities in the CTSA-sponsored clinical research environment. The medical informatics initiative eliminated typewritten or handwritten medication orders, created research protocol-specific templates meeting institutional order-writing requirements, and formalized a rigorous review and approval process. Enhancing safety in medication ordering and prescribing practices in a clinical research environment provided the background for multidisciplinary cooperation in medical informatics.

摘要

虽然临床医学通常得到卫生系统信息技术基础设施的良好支持,但临床研究可能需要制定策略来使用临床医学信息技术工具。作者描述了一项药物安全计划,该计划在 NIH 临床与转化科学奖 (CTSA) 赞助的临床研究环境中实施。设计并实现了一个基于网络的医学信息学应用程序,使研究小组能够构建特定于协议的电子药物模板,然后用于为 CTSA 赞助的临床研究环境中的临床研究活动创建特定于参与者的药物医嘱集。医学信息学计划消除了手写或手写信件的药物医嘱,创建了符合机构医嘱书写要求的研究协议特定模板,并使严格的审查和批准过程正式化。在临床研究环境中提高药物开具和处方实践的安全性为医学信息学中的多学科合作提供了背景。

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Implementing a standardized order set for community-acquired pneumonia: impact on mortality and cost.实施社区获得性肺炎标准化医嘱集:对死亡率和成本的影响。
Jt Comm J Qual Patient Saf. 2009 Aug;35(8):414-21. doi: 10.1016/s1553-7250(09)35058-8.
2
Preprinted order sets as a safety intervention in pediatric sedation.预印医嘱集作为儿科镇静的一种安全干预措施。
J Pediatr. 2009 Jun;154(6):865-8. doi: 10.1016/j.jpeds.2008.12.022. Epub 2009 Feb 1.
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The effect of electronic prescribing on medication errors and adverse drug events: a systematic review.电子处方对用药错误和药物不良事件的影响:系统评价。
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Implementation of standard order sets for patient-controlled analgesia.患者自控镇痛标准医嘱集的实施。
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Medication order communication using fax and document-imaging technologies.使用传真和文档成像技术进行用药医嘱沟通。
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The art and science of preprinted physician orders.预印医生医嘱的艺术与科学。
J Healthc Qual. 2007 Nov-Dec;29(6):7-11, 32. doi: 10.1111/j.1945-1474.2007.tb00219.x.
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Effect of preprinted order form on epoetin alfa prescribing.预印订单表格对促红细胞生成素α处方的影响。
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Cost-effectiveness of an electronic medication ordering and administration system in reducing adverse drug events.电子医嘱与给药系统在减少药物不良事件方面的成本效益
J Eval Clin Pract. 2007 Jun;13(3):440-8. doi: 10.1111/j.1365-2753.2006.00738.x.
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Effect of computerisation on the quality and safety of chemotherapy prescription.计算机化对化疗处方质量与安全性的影响。
Qual Saf Health Care. 2006 Dec;15(6):418-21. doi: 10.1136/qshc.2005.016808.
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Using preprinted medication order forms to improve the safety of investigational drug use.使用预先印制的用药医嘱单来提高研究性药物使用的安全性。
Am J Health Syst Pharm. 2006 Jun 1;63(11):1022, 1025-6, 1028. doi: 10.2146/ajhp060037.