Pine J K, Goldsmith P J, Ridgway D M, Pollard S G, Menon K V, Attia M, Ahmad N
Department of Transplant Surgery, St. James University Hospital, Leeds, West Yorkshire, United Kingdom.
Transplant Proc. 2010 Dec;42(10):3949-50. doi: 10.1016/j.transproceed.2010.09.080.
Donation after cardiac death donation allows donor pool expansion. The period between withdrawal of treatment and donor a systole is extremely variable; its prolongation often results in unsuccessful organ procurement. We sought to assess a variety of donor variables to determine whether they predicted successful organ retrieval. We included all Donation after Cardiac Death (DCD) retrievals between 2002 and 2009, which were grouped as successful (n = 104) versus unsuccessful (n = 42). Factors that predicted unsuccessful organ procurement included older donor age, donor history of hypertension, higher at withdrawal, and absence of inotropic support. On multivariate analysis, mean arterial pressure retained its significance. Prediction of withdrawal-to-asystole time is complex, but our analysis suggested that donor blood pressure at withdrawal is an important predictor of whether retrieval would be successful.
心脏死亡后捐赠可扩大供体库。从停止治疗到供体心脏停搏的时间差异极大；其延长往往导致器官获取失败。我们试图评估各种供体变量，以确定它们是否能预测器官获取成功。我们纳入了2002年至2009年间所有心脏死亡后捐赠（DCD）的案例，分为成功组（n = 104）和失败组（n = 42）。预测器官获取失败的因素包括供体年龄较大、有高血压病史、停止治疗时血压较高以及缺乏血管活性药物支持。多因素分析显示，平均动脉压仍具有显著意义。预测从停止治疗到心脏停搏的时间很复杂，但我们的分析表明，停止治疗时的供体血压是获取是否成功的重要预测指标。
