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亲属活体肾移植项目中新发糖尿病发生的危险因素。

Risk factors for the development of new-onset diabetes mellitus in a living related renal transplant program.

作者信息

Bora G S, Guleria S, Reddy V S, Tandon N, Gupta N, Gupta S, Bhowmik D

机构信息

Department of Surgery, Endocrinology and Nephrology, All India Institute of Medical Sciences, Ansari Nagar, 110029 New Delhi, India.

出版信息

Transplant Proc. 2010 Dec;42(10):4072-3. doi: 10.1016/j.transproceed.2010.10.008.

Abstract

New-onset diabetes mellitus is associated with considerable morbidity after transplantation. We evaluated 78 living related renal transplant recipients due to all causes except diabetic nephropathy a waiting a living related renal transplantation. We evaluated demographic characteristics, pretransplant glycemic profile, fasting C-peptide levels, plasma insulin levels, pretransplant insulin resistance, and immunosuppression protocols. Among the 16.7% of patients developing diabetes mellitus at the end of 1 year, age, family history, and impaired glucose tolerance at the time of transplantation correlated with the development of diabetes mellitus in the posttransplant period.

摘要

新发糖尿病与移植后相当高的发病率相关。我们评估了78例因除糖尿病肾病外的所有病因等待亲属活体肾移植的受者。我们评估了人口统计学特征、移植前血糖谱、空腹C肽水平、血浆胰岛素水平、移植前胰岛素抵抗和免疫抑制方案。在1年后发生糖尿病的患者中,16.7%的患者的年龄、家族史以及移植时糖耐量受损与移植后糖尿病的发生相关。

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