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经导管主动脉瓣植入术,患者选择过程和程序:两个中心在无全身麻醉情况下的干预经验。

Transcatheter aortic valve implantation, patient selection process and procedure: two centres' experience of the intervention without general anaesthesia.

机构信息

First Department of Cardiology, Hippokration Hospital, National & Kapodistrian University of Athens, Greece.

出版信息

Hellenic J Cardiol. 2010 Nov-Dec;51(6):492-500.

Abstract

INTRODUCTION

transcatheter aortic valve implantation (TAVI) is an emerging technique for the treatment of aortic stenosis. With the advent of percutaneous suture devices for the access point and prosthesis delivery systems of smaller diameter, TAVI has become a truly percutaneous procedure: percutaneous aortic valve replacement (PAVR). Thus, PAVR may be conducted without general anaesthesia (GA).

METHODS

We report two centres' experience from PAVR without GA. CoreValve aortic bioprostheses were utilised. The patient selection process and PAVR procedure are described in detail.

RESULTS

a total of 30 patients (pts) were treated with PAVR. In 4 pts correction of the initial malposition of the prosthesis required a special technique (2 pts: "snare"; 2 pts: "removing and reinserting"). At 1-month follow up, haemodynamic and clinical improvements were observed: left ventricular ejection fraction increased from 50.8 ± 9.3% to 54.3 ± 8.3% (p=0.02); peak aortic valve gradient decreased from 90.3 ± 26.4 mmHg to 14.8 ± 9.7 mmHg, (p<0.001); NYHA functional class decreased from 3.53 ± 0.93 to 1.45 ± 0.94 (p<0.001). Overall 1-month mortality was 3.3% (1 patient died).

CONCLUSION

PAVR without general anaesthesia is a feasible technique, however the role of anaesthesiologists is still important.

摘要

介绍

经导管主动脉瓣植入术(TAVI)是治疗主动脉瓣狭窄的新兴技术。随着经皮缝合器用于入路和更小直径的假体输送系统的出现,TAVI 已成为真正的经皮手术:经皮主动脉瓣置换术(PAVR)。因此,PAVR 可以在不使用全身麻醉(GA)的情况下进行。

方法

我们报告了两个中心在不使用 GA 的情况下进行 PAVR 的经验。使用 CoreValve 主动脉生物假体。详细描述了患者选择过程和 PAVR 程序。

结果

共 30 例患者接受了 PAVR 治疗。在 4 例患者中,假体的初始位置不正需要特殊技术进行纠正(2 例:“套索”;2 例:“取出并重新插入”)。在 1 个月的随访中,观察到血液动力学和临床改善:左心室射血分数从 50.8 ± 9.3%增加到 54.3 ± 8.3%(p=0.02);峰值主动脉瓣梯度从 90.3 ± 26.4mmHg 降低至 14.8 ± 9.7mmHg,(p<0.001);纽约心脏协会功能分级从 3.53 ± 0.93 降低至 1.45 ± 0.94(p<0.001)。总的 1 个月死亡率为 3.3%(1 例死亡)。

结论

在不使用全身麻醉的情况下进行 PAVR 是可行的技术,但是麻醉师的作用仍然很重要。

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