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[载脂蛋白A-I/二棕榈酰磷脂酰胆碱脂质体对兔和树鼩培养平滑肌细胞中³H-胆固醇的清除作用]

[Clearance effect of 3H-cholesterol by Apo-AI/DPPC liposome from cultured SMC of rabbits and tree shrew].

作者信息

Cai C B

机构信息

Department of Pathology, Faculty of Basic Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing.

出版信息

Zhonghua Bing Li Xue Za Zhi. 1990 Mar;19(1):12-5.

PMID:2116940
Abstract

Micellar liposomes were prepared by using Apo-AI from rabbit or tree shrew and dipalmitoylphosphatidyl choline (DPPC), with or without cholesterol through a rapid dialysis method. An obvious ability was noticed in clearing of 3H-cholesterol from the cultured smooth muscle cells (SMC) and a cross effect of Apo-AI originated from either rabbit's or tree shrew's serum on the clearance rate of 3H-cholesterol from the cultured SMC of these two species of animals was also obtained.

摘要

通过快速透析法,使用来自兔或树鼩的载脂蛋白A-I(Apo-AI)和二棕榈酰磷脂酰胆碱(DPPC),添加或不添加胆固醇来制备胶束脂质体。观察到其对培养的平滑肌细胞(SMC)中³H-胆固醇具有明显的清除能力,并且还获得了源自兔或树鼩血清的Apo-AI对这两种动物培养的SMC中³H-胆固醇清除率的交叉影响。

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