维生素D对T细胞活化的调控 - Suppr

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Control of T cell activation by vitamin D.

作者信息

Smolders Joost, Thewissen Mariëlle, Damoiseaux Jan

出版信息

Nat Immunol. 2011 Jan;12(1):3; author reply 3-4. doi: 10.1038/ni0111-3a.

DOI:10.1038/ni0111-3a

PMID:21169995

Abstract

摘要

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Control of T cell activation by vitamin D.维生素D对T细胞活化的调控

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本文引用的文献

Vitamin D controls T cell antigen receptor signaling and activation of human T cells.维生素 D 控制 T 细胞抗原受体信号和人类 T 细胞的激活。

Nat Immunol. 2010 Apr;11(4):344-9. doi: 10.1038/ni.1851. Epub 2010 Mar 7.

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.1,25-二羟基维生素D3与白细胞介素-2联合抑制T细胞炎性细胞因子的产生，并促进表达细胞毒性T淋巴细胞相关抗原4（CTLA-4）和叉头框蛋白3（FoxP3）的调节性T细胞的发育。

J Immunol. 2009 Nov 1;183(9):5458-67. doi: 10.4049/jimmunol.0803217.

On the mechanism underlying (23S)-25-dehydro-1alpha(OH)-vitamin D3-26,23-lactone antagonism of hVDRwt gene activation and its switch to a superagonist.在（23S）-25-去氢-1α（OH）-维生素 D3-26,23-内酯拮抗 hVDRwt 基因激活及其向超激动剂转变的机制。

J Biol Chem. 2009 Dec 25;284(52):36292-36301. doi: 10.1074/jbc.M109.042069. Epub 2009 Sep 28.

Immunomodulatory effects of Vitamin D in multiple sclerosis.维生素D在多发性硬化症中的免疫调节作用。

Brain. 2009 May;132(Pt 5):1146-60. doi: 10.1093/brain/awp033. Epub 2009 Mar 24.

Immunomodulation by a novel, dissociated Vitamin D analogue.一种新型解离型维生素D类似物的免疫调节作用

Exp Dermatol. 2009 Jul;18(7):619-27. doi: 10.1111/j.1600-0625.2009.00845.x. Epub 2009 Feb 23.

A novel immunosuppressive 1alpha,25-dihydroxyvitamin D3 analog with reduced hypercalcemic activity.一种具有降低高钙血症活性的新型免疫抑制性1α,25-二羟基维生素D3类似物。

J Invest Dermatol. 2002 Dec;119(6):1434-42. doi: 10.1046/j.1523-1747.2002.19623.x.

Inhibition by ketoconazole of mitogen-induced DNA synthesis and cholesterol biosynthesis in lymphocytes.酮康唑对淋巴细胞中丝裂原诱导的DNA合成和胆固醇生物合成的抑制作用。

Antimicrob Agents Chemother. 1983 Oct;24(4):478-85. doi: 10.1128/AAC.24.4.478.

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